CRISPR/Cas13 as a Tool for RNA Interference

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59 Scopus citations

Abstract

Almost all biological processes involve RNA, making it crucial to develop tools for manipulation of the transcriptome. The bacterial CRISPR/Cas13 system was recently rewired to facilitate RNA manipulation in eukaryotes, including plants. We discuss here the opportunities and limitations of using CRISPR/Cas13 in plants for various types of RNA manipulation.
Original languageEnglish (US)
Pages (from-to)374-378
Number of pages5
JournalTrends in Plant Science
Volume23
Issue number5
DOIs
StatePublished - Mar 28 2018

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledged KAUST grant number(s): OSR-2015-CRG4-2647
Acknowledgements: We wish to thank the Office of Sponsored Research (OSR) and King Abdullah University of Science and Technology (KAUST) for their support (award OSR-2015-CRG4-2647).

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