CRISPR-TSKO: A Tool for Tissue-Specific Genome Editing in Plants.

Zahir Ali; Magdy M. Mahfouz; Shahid Mansoor

doi:10.1016/j.tplants.2019.12.002

CRISPR-TSKO: A Tool for Tissue-Specific Genome Editing in Plants.

Zahir Ali, Magdy M. Mahfouz, Shahid Mansoor

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Functional genomics is at the core of studying the exact function of genes. However, homozygous knockouts of essential and pleiotropic effectors (almost 10% of the genome) are not always possible, thus, functions of these genes remain obscured. The tissue-specific genome editing tool (CRISPR-TSKO) recently described by Decaestecker et al., can characterize these indispensable genes and has wide applications in plants.

Original language	English (US)
Pages (from-to)	123-126
Number of pages	4
Journal	Trends in plant science
Volume	25
Issue number	2
DOIs	https://doi.org/10.1016/j.tplants.2019.12.002
State	Published - Dec 16 2019

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: This work in the lab of S.M. is supported by a research grant from Higher Education Commission, Government of Pakistan.

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10.1016/j.tplants.2019.12.002

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title = "CRISPR-TSKO: A Tool for Tissue-Specific Genome Editing in Plants.",

abstract = "Functional genomics is at the core of studying the exact function of genes. However, homozygous knockouts of essential and pleiotropic effectors (almost 10% of the genome) are not always possible, thus, functions of these genes remain obscured. The tissue-specific genome editing tool (CRISPR-TSKO) recently described by Decaestecker et al., can characterize these indispensable genes and has wide applications in plants.",

author = "Zahir Ali and Mahfouz, {Magdy M.} and Shahid Mansoor",

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AU - Ali, Zahir

AU - Mahfouz, Magdy M.

AU - Mansoor, Shahid

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N2 - Functional genomics is at the core of studying the exact function of genes. However, homozygous knockouts of essential and pleiotropic effectors (almost 10% of the genome) are not always possible, thus, functions of these genes remain obscured. The tissue-specific genome editing tool (CRISPR-TSKO) recently described by Decaestecker et al., can characterize these indispensable genes and has wide applications in plants.

AB - Functional genomics is at the core of studying the exact function of genes. However, homozygous knockouts of essential and pleiotropic effectors (almost 10% of the genome) are not always possible, thus, functions of these genes remain obscured. The tissue-specific genome editing tool (CRISPR-TSKO) recently described by Decaestecker et al., can characterize these indispensable genes and has wide applications in plants.

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ER -

CRISPR-TSKO: A Tool for Tissue-Specific Genome Editing in Plants.

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