CRISPR-Based Directed Evolution for Crop Improvement.

Haroon Butt, Syed Shan-e-Ali Zaidi, Norhan Hassan, Magdy M. Mahfouz

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Directed evolution involves generating diverse sequence variants of a gene of interest to produce a desirable trait under selective pressure. CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR-associated protein 9) systems can be programmed to target any genomic locus and perform targeted directed evolution. Here, we discuss the opportunities and challenges of this emerging platform for targeted crop improvement.
Original languageEnglish (US)
JournalTrends in biotechnology
StatePublished - Aug 30 2019

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01


Dive into the research topics of 'CRISPR-Based Directed Evolution for Crop Improvement.'. Together they form a unique fingerprint.

Cite this