Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent

Xiaoxi Lin; Guimei Wang; Huaifeng Li; Yuanyuan Huang; Weiming He; Dandan Ye; Kuo-Wei Huang; Yaofeng Yuan; Zhiqiang Weng

doi:10.1016/j.tet.2013.01.041

Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent

Xiaoxi Lin, Guimei Wang, Huaifeng Li, Yuanyuan Huang, Weiming He, Dandan Ye, Kuo-Wei Huang, Yaofeng Yuan, Zhiqiang Weng

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

A copper-catalyzed method for the trifluoromethylation of arylsulfinates with Togni's reagent has been developed, affording aryltrifluoromethylsulfones in moderate to good yields. A wide range of functional groups in arylsulfinates are compatible with the reaction conditions. © 2013 Elsevier Ltd. All rights reserved.

Original language	English (US)
Pages (from-to)	2628-2632
Number of pages	5
Journal	Tetrahedron
Volume	69
Issue number	12
DOIs	https://doi.org/10.1016/j.tet.2013.01.041
State	Published - Mar 2013

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We acknowledge the financial support from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W. and King Abdullah University of Science and Technology to K.-W.H.

ASJC Scopus subject areas

Biochemistry
Organic Chemistry
Drug Discovery

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10.1016/j.tet.2013.01.041

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title = "Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent",

abstract = "A copper-catalyzed method for the trifluoromethylation of arylsulfinates with Togni's reagent has been developed, affording aryltrifluoromethylsulfones in moderate to good yields. A wide range of functional groups in arylsulfinates are compatible with the reaction conditions. {\textcopyright} 2013 Elsevier Ltd. All rights reserved.",

author = "Xiaoxi Lin and Guimei Wang and Huaifeng Li and Yuanyuan Huang and Weiming He and Dandan Ye and Kuo-Wei Huang and Yaofeng Yuan and Zhiqiang Weng",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We acknowledge the financial support from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W. and King Abdullah University of Science and Technology to K.-W.H.",

year = "2013",

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doi = "10.1016/j.tet.2013.01.041",

language = "English (US)",

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pages = "2628--2632",

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T1 - Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent

AU - Lin, Xiaoxi

AU - Wang, Guimei

AU - Li, Huaifeng

AU - Huang, Yuanyuan

AU - He, Weiming

AU - Ye, Dandan

AU - Huang, Kuo-Wei

AU - Yuan, Yaofeng

AU - Weng, Zhiqiang

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We acknowledge the financial support from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W. and King Abdullah University of Science and Technology to K.-W.H.

PY - 2013/3

Y1 - 2013/3

N2 - A copper-catalyzed method for the trifluoromethylation of arylsulfinates with Togni's reagent has been developed, affording aryltrifluoromethylsulfones in moderate to good yields. A wide range of functional groups in arylsulfinates are compatible with the reaction conditions. © 2013 Elsevier Ltd. All rights reserved.

AB - A copper-catalyzed method for the trifluoromethylation of arylsulfinates with Togni's reagent has been developed, affording aryltrifluoromethylsulfones in moderate to good yields. A wide range of functional groups in arylsulfinates are compatible with the reaction conditions. © 2013 Elsevier Ltd. All rights reserved.

UR - http://hdl.handle.net/10754/562672

UR - https://linkinghub.elsevier.com/retrieve/pii/S0040402013001026

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DO - 10.1016/j.tet.2013.01.041

M3 - Article

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SP - 2628

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JO - Tetrahedron

JF - Tetrahedron

IS - 12

ER -

Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent

Abstract

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