Convergence of Multiple MAP3Ks on MKK3 Identifies a Set of Novel Stress MAPK Modules

Jean Colcombet, Cécile Sözen, Heribert Hirt

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Since its first description in 1995 and functional characterization 12 years later, plant MKK3-type MAP2Ks have emerged as important integrators in plant signaling. Although they have received less attention than the canonical stress-activated mitogen-activated protein kinases (MAPKs), several recent publications shed light on their important roles in plant adaptation to environmental conditions. Nevertheless, the MKK3-related literature is complicated. This review summarizes the current knowledge and discrepancies on MKK3 MAPK modules in plants and highlights the singular role of MKK3 in green plants. In the light of the latest data, we hypothesize a general model that all clade-III MAP3Ks converge on MKK3 and C-group MAPKs, thereby defining a set of novel MAPK modules which are activated by stresses and internal signals through the transcriptional regulation of MAP3K genes.
Original languageEnglish (US)
JournalFrontiers in Plant Science
Volume07
Issue numberDECEMBER2016
DOIs
StatePublished - Dec 22 2016

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: This work has benefited from a grant (LabEx Saclay Plant Sciences-SPS, reference ANR-10-LABX-0040-SPS), managed by the French National Research Agency under an Investments for the Future program (reference no. ANR-I l-IDEX-0003-02).

Fingerprint

Dive into the research topics of 'Convergence of Multiple MAP3Ks on MKK3 Identifies a Set of Novel Stress MAPK Modules'. Together they form a unique fingerprint.

Cite this