Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes

Keyphrases

• DNA Breaks 100%
• Oncogenic Translocations 100%
• Cancer Susceptibility 50%
• Complex Chromosomal Aberrations 50%
• Complex Chromosomal Rearrangement 50%
• Complex Lesions 50%
• Complex Rearrangement 50%
• Risk Factors 50%
• Solid Cancer 50%
• Genomic Elements 50%
• Immunoglobulin Heavy Chain Locus 50%
• Immunoglobulin Heavy Chain 50%
• MYC Oncogene 50%
• DNA Double-strand Break Repair 50%
• Cancer Marker 50%

Biochemistry, Genetics and Molecular Biology

• Heavy Chain 100%
• Chromosomal Aberration 100%
• Immunoglobulin 100%
• Lymphocyte 100%
• Gene Amplification 100%
• Mouse Model 50%
• Chromosomal Rearrangement 50%
• Genome Instability 50%
• Chromosome Instability 50%
• Enhancer Region 50%
• Oncogene C Myc 50%
• Chromosome Rearrangement 50%