Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment

Jessica L. Clarke; Jeffrey L. Anderson; John F. Carlquist; Richard F. Roberts; Benjamin D. Horne; Tami L. Bair; Matthew J. Kolek; Chrissa P. Mower; Ashle M. Crane; William L. Roberts; Joseph B. Muhlestein

doi:10.1016/j.amjcard.2004.08.087

Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment

Jessica L. Clarke, Jeffrey L. Anderson, John F. Carlquist, Richard F. Roberts, Benjamin D. Horne, Tami L. Bair, Matthew J. Kolek, Chrissa P. Mower, Ashle M. Crane, William L. Roberts, Joseph B. Muhlestein

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

A medium-sensitivity assay for C-reactive protein (CRP) was compared with a high-sensitivity, enhanced immunoturbidimetric assay in 803 angiographically studied patients. Different absolute CRP values were found by the assays, but there was a high correlation by quartile rank and similar predictive values for death and myocardial infarction. This suggests that the conclusions of previous studies performed using the medium-sensitivity assay are still valid but that cross-study comparisons should use percentile rank. © 2005 by Excerpta Medica Inc.

Original language	English (US)
Pages (from-to)	155-158
Number of pages	4
Journal	American Journal of Cardiology
Volume	95
Issue number	1
DOIs	https://doi.org/10.1016/j.amjcard.2004.08.087
State	Published - Jan 1 2005
Externally published	Yes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2023-09-20

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1016/j.amjcard.2004.08.087

Cite this

Clarke, J. L., Anderson, J. L., Carlquist, J. F., Roberts, R. F., Horne, B. D., Bair, T. L., Kolek, M. J., Mower, C. P., Crane, A. M., Roberts, W. L., & Muhlestein, J. B. (2005). Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment. American Journal of Cardiology, 95(1), 155-158. https://doi.org/10.1016/j.amjcard.2004.08.087

@article{00b16eaa4575486baeec989c003da5d9,

title = "Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment",

abstract = "A medium-sensitivity assay for C-reactive protein (CRP) was compared with a high-sensitivity, enhanced immunoturbidimetric assay in 803 angiographically studied patients. Different absolute CRP values were found by the assays, but there was a high correlation by quartile rank and similar predictive values for death and myocardial infarction. This suggests that the conclusions of previous studies performed using the medium-sensitivity assay are still valid but that cross-study comparisons should use percentile rank. {\textcopyright} 2005 by Excerpta Medica Inc.",

author = "Clarke, {Jessica L.} and Anderson, {Jeffrey L.} and Carlquist, {John F.} and Roberts, {Richard F.} and Horne, {Benjamin D.} and Bair, {Tami L.} and Kolek, {Matthew J.} and Mower, {Chrissa P.} and Crane, {Ashle M.} and Roberts, {William L.} and Muhlestein, {Joseph B.}",

note = "Generated from Scopus record by KAUST IRTS on 2023-09-20",

year = "2005",

month = jan,

day = "1",

doi = "10.1016/j.amjcard.2004.08.087",

language = "English (US)",

volume = "95",

pages = "155--158",

journal = "American Journal of Cardiology",

issn = "0002-9149",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment

AU - Clarke, Jessica L.

AU - Anderson, Jeffrey L.

AU - Carlquist, John F.

AU - Roberts, Richard F.

AU - Horne, Benjamin D.

AU - Bair, Tami L.

AU - Kolek, Matthew J.

AU - Mower, Chrissa P.

AU - Crane, Ashle M.

AU - Roberts, William L.

AU - Muhlestein, Joseph B.

N1 - Generated from Scopus record by KAUST IRTS on 2023-09-20

PY - 2005/1/1

Y1 - 2005/1/1

N2 - A medium-sensitivity assay for C-reactive protein (CRP) was compared with a high-sensitivity, enhanced immunoturbidimetric assay in 803 angiographically studied patients. Different absolute CRP values were found by the assays, but there was a high correlation by quartile rank and similar predictive values for death and myocardial infarction. This suggests that the conclusions of previous studies performed using the medium-sensitivity assay are still valid but that cross-study comparisons should use percentile rank. © 2005 by Excerpta Medica Inc.

AB - A medium-sensitivity assay for C-reactive protein (CRP) was compared with a high-sensitivity, enhanced immunoturbidimetric assay in 803 angiographically studied patients. Different absolute CRP values were found by the assays, but there was a high correlation by quartile rank and similar predictive values for death and myocardial infarction. This suggests that the conclusions of previous studies performed using the medium-sensitivity assay are still valid but that cross-study comparisons should use percentile rank. © 2005 by Excerpta Medica Inc.

UR - https://linkinghub.elsevier.com/retrieve/pii/S0002914904014717

UR - http://www.scopus.com/inward/record.url?scp=20244368909&partnerID=8YFLogxK

U2 - 10.1016/j.amjcard.2004.08.087

DO - 10.1016/j.amjcard.2004.08.087

M3 - Article

SN - 0002-9149

VL - 95

SP - 155

EP - 158

JO - American Journal of Cardiology

JF - American Journal of Cardiology

IS - 1

ER -

Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment

Abstract

Bibliographical note

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this