Combinatorial 'library on bead' approach to polymeric materials with vastly enhanced chiral recognition

Peter Murer; Kevin Lewandowski; Frantisek Svec; Jean M.J. Fréchet

doi:10.1039/a806397d

Combinatorial 'library on bead' approach to polymeric materials with vastly enhanced chiral recognition

Peter Murer, Kevin Lewandowski, Frantisek Svec, Jean M.J. Fréchet^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

A general screening method for enantiomer recognition is introduced for the rapid preparation of novel chiral stationary phases for HPLC in which libraries of mixed chiral selectors are immobilized on polymer beads and the resulting chiral phases tested in the separation of racemic targets followed by deconvolution to afford an optimized separation medium.

Original language	English (US)
Pages (from-to)	2559-2560
Number of pages	2
Journal	CHEMICAL COMMUNICATIONS
Issue number	23
DOIs	https://doi.org/10.1039/a806397d
State	Published - Dec 7 1998
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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10.1039/a806397d

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title = "Combinatorial 'library on bead' approach to polymeric materials with vastly enhanced chiral recognition",

abstract = "A general screening method for enantiomer recognition is introduced for the rapid preparation of novel chiral stationary phases for HPLC in which libraries of mixed chiral selectors are immobilized on polymer beads and the resulting chiral phases tested in the separation of racemic targets followed by deconvolution to afford an optimized separation medium.",

author = "Peter Murer and Kevin Lewandowski and Frantisek Svec and Fr{\'e}chet, {Jean M.J.}",

year = "1998",

month = dec,

day = "7",

doi = "10.1039/a806397d",

language = "English (US)",

pages = "2559--2560",

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TY - JOUR

T1 - Combinatorial 'library on bead' approach to polymeric materials with vastly enhanced chiral recognition

AU - Murer, Peter

AU - Lewandowski, Kevin

AU - Svec, Frantisek

AU - Fréchet, Jean M.J.

PY - 1998/12/7

Y1 - 1998/12/7

N2 - A general screening method for enantiomer recognition is introduced for the rapid preparation of novel chiral stationary phases for HPLC in which libraries of mixed chiral selectors are immobilized on polymer beads and the resulting chiral phases tested in the separation of racemic targets followed by deconvolution to afford an optimized separation medium.

AB - A general screening method for enantiomer recognition is introduced for the rapid preparation of novel chiral stationary phases for HPLC in which libraries of mixed chiral selectors are immobilized on polymer beads and the resulting chiral phases tested in the separation of racemic targets followed by deconvolution to afford an optimized separation medium.

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U2 - 10.1039/a806397d

DO - 10.1039/a806397d

M3 - Article

AN - SCOPUS:0032494970

SN - 1359-7345

SP - 2559

EP - 2560

JO - CHEMICAL COMMUNICATIONS

JF - CHEMICAL COMMUNICATIONS

IS - 23

ER -

Combinatorial 'library on bead' approach to polymeric materials with vastly enhanced chiral recognition

Abstract

ASJC Scopus subject areas

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