Chemo- and Regioselective Magnesium-Catalyzed ortho-Alkenylation of Anilines

Adisak Chatupheeraphat; Magnus Rueping; Marc Magre

doi:10.1021/acs.orglett.9b03526

Chemo- and Regioselective Magnesium-Catalyzed ortho-Alkenylation of Anilines

Adisak Chatupheeraphat, Magnus Rueping, Marc Magre

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32 Scopus citations

Abstract

A simple and efficient catalytic system for a chemo- and regioselective ortho-alkenylation of anilines is presented. The new magnesium-catalyzed reaction allows the use of a wide range of alkynes and anilines with different electronic and steric properties and provides free as well as protected anilines with excellent yields.

Original language	English (US)
Pages (from-to)	9153-9157
Number of pages	5
Journal	Organic Letters
Volume	21
Issue number	22
DOIs	https://doi.org/10.1021/acs.orglett.9b03526
State	Published - Oct 31 2019

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https://repository.kaust.edu.sa/bitstream/10754/659953/1/acs.orglett.9b03526.pdf

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title = "Chemo- and Regioselective Magnesium-Catalyzed ortho-Alkenylation of Anilines",

abstract = "A simple and efficient catalytic system for a chemo- and regioselective ortho-alkenylation of anilines is presented. The new magnesium-catalyzed reaction allows the use of a wide range of alkynes and anilines with different electronic and steric properties and provides free as well as protected anilines with excellent yields.",

author = "Adisak Chatupheeraphat and Magnus Rueping and Marc Magre",

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AU - Chatupheeraphat, Adisak

AU - Rueping, Magnus

AU - Magre, Marc

N1 - KAUST Repository Item: Exported on 2020-10-01

PY - 2019/10/31

Y1 - 2019/10/31

N2 - A simple and efficient catalytic system for a chemo- and regioselective ortho-alkenylation of anilines is presented. The new magnesium-catalyzed reaction allows the use of a wide range of alkynes and anilines with different electronic and steric properties and provides free as well as protected anilines with excellent yields.

AB - A simple and efficient catalytic system for a chemo- and regioselective ortho-alkenylation of anilines is presented. The new magnesium-catalyzed reaction allows the use of a wide range of alkynes and anilines with different electronic and steric properties and provides free as well as protected anilines with excellent yields.

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UR - https://pubs.acs.org/doi/10.1021/acs.orglett.9b03526

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U2 - 10.1021/acs.orglett.9b03526

DO - 10.1021/acs.orglett.9b03526

M3 - Article

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JO - Organic Letters

JF - Organic Letters

IS - 22

ER -

Chemo- and Regioselective Magnesium-Catalyzed ortho-Alkenylation of Anilines

Abstract

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