Characterization of solid UV cross-linked PEGDA for biological applications

David Castro; Patrick Ingram; Rimantas Kodzius; David Conchouso Gonzalez; Euisik Yoon; Ian G. Foulds

doi:10.1109/MEMSYS.2013.6474277

Characterization of solid UV cross-linked PEGDA for biological applications

David Castro, Patrick Ingram, Rimantas Kodzius, David Conchouso Gonzalez, Euisik Yoon, Ian G. Foulds

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

19 Scopus citations

Abstract

This paper reports on solid UV cross-linked Poly(ethylene)-glycol-diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.

Original language	English (US)
Title of host publication	2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
Pages	457-460
Number of pages	4
ISBN (Print)	978-146735655-8
DOIs	https://doi.org/10.1109/MEMSYS.2013.6474277
State	Published - Mar 20 2013

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01

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10.1109/MEMSYS.2013.6474277

https://repository.kaust.edu.sa/bitstream/10754/303702/1/Characterization%20of%20Solid%20UV%20Cross-Linked%20PEGDA%20for%20Biological%20Applications%20049-Mo.pdf

Cite this

Castro, D., Ingram, P., Kodzius, R., Conchouso Gonzalez, D., Yoon, E., & Foulds, I. G. (2013). Characterization of solid UV cross-linked PEGDA for biological applications. In 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 457-460). Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/MEMSYS.2013.6474277

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title = "Characterization of solid UV cross-linked PEGDA for biological applications",

abstract = "This paper reports on solid UV cross-linked Poly(ethylene)-glycol-diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.",

author = "David Castro and Patrick Ingram and Rimantas Kodzius and {Conchouso Gonzalez}, David and Euisik Yoon and Foulds, {Ian G.}",

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year = "2013",

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doi = "10.1109/MEMSYS.2013.6474277",

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Characterization of solid UV cross-linked PEGDA for biological applications. / Castro, David; Ingram, Patrick; Kodzius, Rimantas et al.
2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS). Institute of Electrical and Electronics Engineers (IEEE), 2013. p. 457-460.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Characterization of solid UV cross-linked PEGDA for biological applications

AU - Castro, David

AU - Ingram, Patrick

AU - Kodzius, Rimantas

AU - Conchouso Gonzalez, David

AU - Yoon, Euisik

AU - Foulds, Ian G.

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PY - 2013/3/20

Y1 - 2013/3/20

N2 - This paper reports on solid UV cross-linked Poly(ethylene)-glycol-diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.

AB - This paper reports on solid UV cross-linked Poly(ethylene)-glycol-diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.

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BT - 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)

PB - Institute of Electrical and Electronics Engineers (IEEE)

ER -

Characterization of solid UV cross-linked PEGDA for biological applications

Abstract

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