Catalytic Ester and Amide to Amine Interconversion: Nickel-Catalyzed Decarbonylative Amination of Esters and Amides by C−O and C−C Bond Activation

Huifeng Yue; Lin Guo; Hsuan-Hung Liao; Yunfei Cai; Chen Zhu; Magnus Rueping

doi:10.1002/anie.201611819

Catalytic Ester and Amide to Amine Interconversion: Nickel-Catalyzed Decarbonylative Amination of Esters and Amides by C−O and C−C Bond Activation

Huifeng Yue, Lin Guo, Hsuan-Hung Liao, Yunfei Cai, Chen Zhu, Magnus Rueping

Research output: Contribution to journal › Article › peer-review

147 Scopus citations

Abstract

An efficient nickel-catalyzed decarbonylative amination reaction of aryl and heteroaryl esters has been achieved for the first time. The new amination protocol allows the direct interconversion of esters and amides into the corresponding amines and represents a good alternative to classical rearrangements as well as cross coupling reactions.

Original language	English (US)
Pages (from-to)	4282-4285
Number of pages	4
Journal	Angewandte Chemie International Edition
Volume	56
Issue number	15
DOIs	https://doi.org/10.1002/anie.201611819 https://doi.org/10.1002/ange.201611819
State	Published - Mar 15 2017

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: H.Y. and L.G. acknowledge the China Scholarship Council. H.-H.L. acknowledges the DAAD for a doctoral fellowship, Y.C. acknowledges the Alexander von Humboldt-Foundation for a fellowship. Support by King Abdullah University of Science and Technology (KAUST) is gratefully acknowledged.

Access to Document

https://repository.kaust.edu.sa/bitstream/10754/623218/1/Manuscript_Accepted.pdf

Cite this

@article{8c78d994f6204c638675c4a9247c23a2,

title = "Catalytic Ester and Amide to Amine Interconversion: Nickel-Catalyzed Decarbonylative Amination of Esters and Amides by C−O and C−C Bond Activation",

abstract = "An efficient nickel-catalyzed decarbonylative amination reaction of aryl and heteroaryl esters has been achieved for the first time. The new amination protocol allows the direct interconversion of esters and amides into the corresponding amines and represents a good alternative to classical rearrangements as well as cross coupling reactions.",

author = "Huifeng Yue and Lin Guo and Hsuan-Hung Liao and Yunfei Cai and Chen Zhu and Magnus Rueping",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: H.Y. and L.G. acknowledge the China Scholarship Council. H.-H.L. acknowledges the DAAD for a doctoral fellowship, Y.C. acknowledges the Alexander von Humboldt-Foundation for a fellowship. Support by King Abdullah University of Science and Technology (KAUST) is gratefully acknowledged.",

year = "2017",

month = mar,

day = "15",

doi = "10.1002/anie.201611819",

language = "English (US)",

volume = "56",

pages = "4282--4285",

journal = "Angewandte Chemie International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "15",

}

TY - JOUR

T1 - Catalytic Ester and Amide to Amine Interconversion: Nickel-Catalyzed Decarbonylative Amination of Esters and Amides by C−O and C−C Bond Activation

AU - Yue, Huifeng

AU - Guo, Lin

AU - Liao, Hsuan-Hung

AU - Cai, Yunfei

AU - Zhu, Chen

AU - Rueping, Magnus

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: H.Y. and L.G. acknowledge the China Scholarship Council. H.-H.L. acknowledges the DAAD for a doctoral fellowship, Y.C. acknowledges the Alexander von Humboldt-Foundation for a fellowship. Support by King Abdullah University of Science and Technology (KAUST) is gratefully acknowledged.

PY - 2017/3/15

Y1 - 2017/3/15

N2 - An efficient nickel-catalyzed decarbonylative amination reaction of aryl and heteroaryl esters has been achieved for the first time. The new amination protocol allows the direct interconversion of esters and amides into the corresponding amines and represents a good alternative to classical rearrangements as well as cross coupling reactions.

AB - An efficient nickel-catalyzed decarbonylative amination reaction of aryl and heteroaryl esters has been achieved for the first time. The new amination protocol allows the direct interconversion of esters and amides into the corresponding amines and represents a good alternative to classical rearrangements as well as cross coupling reactions.

UR - http://hdl.handle.net/10754/623218

UR - http://onlinelibrary.wiley.com/doi/10.1002/anie.201611819/full

UR - http://www.scopus.com/inward/record.url?scp=85015237827&partnerID=8YFLogxK

U2 - 10.1002/anie.201611819

DO - 10.1002/anie.201611819

M3 - Article

C2 - 28294473

SN - 1433-7851

VL - 56

SP - 4282

EP - 4285

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

IS - 15

ER -

Catalytic Ester and Amide to Amine Interconversion: Nickel-Catalyzed Decarbonylative Amination of Esters and Amides by C−O and C−C Bond Activation

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this