Catalytic C1  Alkylation with Methanol and Isotope-Labeled Methanol

Jan Sklyaruk, Jannik C. Borghs, Osama El-Sepelgy, Magnus Rueping

Research output: Contribution to journalArticlepeer-review

100 Scopus citations


A metal-catalyzed methylation process has been developed. By employing an air- and moisture-stable manganese catalyst together with isotopically labeled methanol, a series of D-, CD-, and C-labeled products were obtained in good yields under mild reaction conditions with water as the only byproduct.
Original languageEnglish (US)
Pages (from-to)775-779
Number of pages5
JournalAngewandte Chemie International Edition
Issue number3
StatePublished - Dec 17 2018

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: J.S. is grateful for a doctoral fellowship provided by the Fonds der Chemischen Industrie. J.C.B. acknowledges the DBU for a doctoral fellowship.


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