Abstract
A catalytic enantioselective synthesis of dihydrofurans has been developed. 1,3-Dicarbonyl derivatives react with (E)-β,β-bromonitrostyrenes in the presence of a chiral bifunctional thiourea catalyst providing mild and efficient access to diverse polysubstituted dihydrofurans in good yields and enantioselectivities.
Original language | English (US) |
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Pages (from-to) | 5680-5683 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 12 |
Issue number | 24 |
DOIs | |
State | Published - Dec 17 2010 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry