Carotenoid Biofortification of Crops in the CRISPR Era

Xiongjie Zheng; Hendrik N.J. Kuijer; Salim Al-Babili

doi:10.1016/j.tibtech.2020.12.003

Carotenoid Biofortification of Crops in the CRISPR Era

Xiongjie Zheng, Hendrik N.J. Kuijer, Salim Al-Babili

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Carotenoids are micronutrients important for human health. The continuous improvements in clustered regularly interspaced short palindromic repeats (CRISPR)-based genome-editing techniques make rapid, DNA/transgene-free and targeted multiplex genetic modification a reality, thus promising to accelerate the breeding and generation of ‘golden’ staple crops. We discuss here the progress and future prospects of CRISPR/Cas9 applications for carotenoid biofortification.

Original language	English (US)
Pages (from-to)	857-860
Number of pages	4
Journal	Trends in Biotechnology
Volume	39
Issue number	9
DOIs	https://doi.org/10.1016/j.tibtech.2020.12.003
State	Published - Dec 29 2020

Bibliographical note

KAUST Repository Item: Exported on 2021-11-24
Acknowledgements: We thank Dr Jianing Mi for valuable discussions and want to apologize to colleagues whose work could not be discussed and cited here due to space limitations. No conflict of interest declared. This work was supported by baseline funding from King Abdullah University of Science and Technology (KAUST), Saudi Arabia.

ASJC Scopus subject areas

Bioengineering
Biotechnology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tibtech.2020.12.003

Cite this

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title = "Carotenoid Biofortification of Crops in the CRISPR Era",

abstract = "Carotenoids are micronutrients important for human health. The continuous improvements in clustered regularly interspaced short palindromic repeats (CRISPR)-based genome-editing techniques make rapid, DNA/transgene-free and targeted multiplex genetic modification a reality, thus promising to accelerate the breeding and generation of {\textquoteleft}golden{\textquoteright} staple crops. We discuss here the progress and future prospects of CRISPR/Cas9 applications for carotenoid biofortification.",

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note = "KAUST Repository Item: Exported on 2021-11-24 Acknowledgements: We thank Dr Jianing Mi for valuable discussions and want to apologize to colleagues whose work could not be discussed and cited here due to space limitations. No conflict of interest declared. This work was supported by baseline funding from King Abdullah University of Science and Technology (KAUST), Saudi Arabia.",

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AU - Kuijer, Hendrik N.J.

AU - Al-Babili, Salim

N1 - KAUST Repository Item: Exported on 2021-11-24 Acknowledgements: We thank Dr Jianing Mi for valuable discussions and want to apologize to colleagues whose work could not be discussed and cited here due to space limitations. No conflict of interest declared. This work was supported by baseline funding from King Abdullah University of Science and Technology (KAUST), Saudi Arabia.

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AB - Carotenoids are micronutrients important for human health. The continuous improvements in clustered regularly interspaced short palindromic repeats (CRISPR)-based genome-editing techniques make rapid, DNA/transgene-free and targeted multiplex genetic modification a reality, thus promising to accelerate the breeding and generation of ‘golden’ staple crops. We discuss here the progress and future prospects of CRISPR/Cas9 applications for carotenoid biofortification.

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Carotenoid Biofortification of Crops in the CRISPR Era

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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