Can modular analysis identify disease-associated candidate genes for therapeutics?

Jesper Tegnér*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review


Complex diseases such as allergy change gene expression in several cell types and tissues. Benson and colleagues have now shown, in a paper in BMC Systems Biology, that this complexity can be studied effectively using an integrated experimental and computational modular analysis. Their strategy revealed a core of allergy-associated genes of potential therapeutic value.

Original languageEnglish (US)
Article number48
JournalJournal of Biology
Issue number5
StatePublished - 2009
Externally publishedYes

Bibliographical note

Funding Information:
I thank the Swedish Research Council for support.

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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