Burden of thyroid cancer in North Africa and Middle East 1990–2019

Seyed Aria Nejadghaderi; Sahar Saeedi Moghaddam; Sina Azadnajafabad; Negar Rezaei; Nazila Rezaei; Seyed Mohammad Tavangar; Hamidreza Jamshidi; Ali H. Mokdad; Mohsen Naghavi; Farshad Farzadfar; Bagher Larijani; GBD 2019 NAME Thyroid Cancer Collaborators; Paula Moraga

doi:10.3389/fonc.2022.955358

Burden of thyroid cancer in North Africa and Middle East 1990–2019

Seyed Aria Nejadghaderi, Sahar Saeedi Moghaddam, Sina Azadnajafabad, Negar Rezaei, Nazila Rezaei, Seyed Mohammad Tavangar, Hamidreza Jamshidi, Ali H. Mokdad, Mohsen Naghavi, Farshad Farzadfar, Bagher Larijani, GBD 2019 NAME Thyroid Cancer Collaborators, Paula Moraga

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4 Scopus citations

Abstract

Background: Thyroid cancer is the leading cause of mortality and morbidity among cancers of the endocrine system. We aimed to describe the trends of thyroid cancer burden in North Africa and Middle East for 1990–2019. Methods: Data on burden of thyroid cancer in North Africa and Middle East from 1990 to 2019 were obtained from the Global Burden of Disease (GBD) Study 2019. Decomposition analysis was used to estimate the effects of population growth, aging, and change in incident numbers on overall change of thyroid cancer incidence. Also, we used the comparative risk assessment framework of GBD to determine the burden of thyroid cancer attributable to a high body mass index (BMI). Results: In 2019, the age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) of thyroid cancer were 3.5 (2.9–4) and 0.5 (0.5–0.7) per 100,000, respectively. The highest age-standardized incidence, deaths, and disability-adjusted life year (DALY) rate were in Lebanon, Afghanistan, and United Arab Emirates, respectively. The ASIR of thyroid cancer in region was about 2.5 times higher among women, which had a positive association with increasing age. In 2019, the age-standardized deaths attributable to a high BMI was 16.7% of all deaths due to thyroid cancer. In 1990–2019, the overall change in thyroid cancer incident cases was a 396% increase which was mostly driven by the increase in disease-specific incidence rate (256.8%). Conclusions: Women, the elderly above about 60 years old, and countries with a higher sociodemographic index showed higher incidence rates of thyroid cancer. Regarding our findings, it is recommended to establish preventive plans by modification in life style like weight reduction programs.

Original language	English (US)
Journal	Frontiers in Oncology
Volume	12
DOIs	https://doi.org/10.3389/fonc.2022.955358
State	Published - Sep 23 2022

Bibliographical note

KAUST Repository Item: Exported on 2022-12-15
Acknowledgements: The Bill and Melinda Gates Foundation, who were not involved in any way in the preparation of this manuscript, funded the GBD study. We would like to thank the Institute for Health Metrics and Evaluation staff and its collaborators who prepared these publicly available data. Z Piracha and U Saeed would like to acknowledge the support of the International Center of Medical Sciences Research, Islamabad (44000), Pakistan. A M Samy acknowledges the support from the Egyptian Fulbright Mission Program and being a member of the Egyptian Young Academy of Sciences.

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3389/fonc.2022.955358

https://repository.kaust.edu.sa/bitstream/10754/686421/1/fonc-12-955358%20%281%29.pdf

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@article{6f57325753254569a74a91c54edacda3,

title = "Burden of thyroid cancer in North Africa and Middle East 1990–2019",

abstract = "Background: Thyroid cancer is the leading cause of mortality and morbidity among cancers of the endocrine system. We aimed to describe the trends of thyroid cancer burden in North Africa and Middle East for 1990–2019. Methods: Data on burden of thyroid cancer in North Africa and Middle East from 1990 to 2019 were obtained from the Global Burden of Disease (GBD) Study 2019. Decomposition analysis was used to estimate the effects of population growth, aging, and change in incident numbers on overall change of thyroid cancer incidence. Also, we used the comparative risk assessment framework of GBD to determine the burden of thyroid cancer attributable to a high body mass index (BMI). Results: In 2019, the age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) of thyroid cancer were 3.5 (2.9–4) and 0.5 (0.5–0.7) per 100,000, respectively. The highest age-standardized incidence, deaths, and disability-adjusted life year (DALY) rate were in Lebanon, Afghanistan, and United Arab Emirates, respectively. The ASIR of thyroid cancer in region was about 2.5 times higher among women, which had a positive association with increasing age. In 2019, the age-standardized deaths attributable to a high BMI was 16.7% of all deaths due to thyroid cancer. In 1990–2019, the overall change in thyroid cancer incident cases was a 396% increase which was mostly driven by the increase in disease-specific incidence rate (256.8%). Conclusions: Women, the elderly above about 60 years old, and countries with a higher sociodemographic index showed higher incidence rates of thyroid cancer. Regarding our findings, it is recommended to establish preventive plans by modification in life style like weight reduction programs.",

author = "Nejadghaderi, {Seyed Aria} and Moghaddam, {Sahar Saeedi} and Sina Azadnajafabad and Negar Rezaei and Nazila Rezaei and Tavangar, {Seyed Mohammad} and Hamidreza Jamshidi and Mokdad, {Ali H.} and Mohsen Naghavi and Farshad Farzadfar and Bagher Larijani and Collaborators, {GBD 2019 NAME Thyroid Cancer} and Paula Moraga",

note = "KAUST Repository Item: Exported on 2022-12-15 Acknowledgements: The Bill and Melinda Gates Foundation, who were not involved in any way in the preparation of this manuscript, funded the GBD study. We would like to thank the Institute for Health Metrics and Evaluation staff and its collaborators who prepared these publicly available data. Z Piracha and U Saeed would like to acknowledge the support of the International Center of Medical Sciences Research, Islamabad (44000), Pakistan. A M Samy acknowledges the support from the Egyptian Fulbright Mission Program and being a member of the Egyptian Young Academy of Sciences.",

year = "2022",

month = sep,

day = "23",

doi = "10.3389/fonc.2022.955358",

language = "English (US)",

volume = "12",

journal = "Frontiers in Oncology",

issn = "2234-943X",

publisher = "Frontiers Media SA",

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TY - JOUR

T1 - Burden of thyroid cancer in North Africa and Middle East 1990–2019

AU - Nejadghaderi, Seyed Aria

AU - Moghaddam, Sahar Saeedi

AU - Azadnajafabad, Sina

AU - Rezaei, Negar

AU - Rezaei, Nazila

AU - Tavangar, Seyed Mohammad

AU - Jamshidi, Hamidreza

AU - Mokdad, Ali H.

AU - Naghavi, Mohsen

AU - Farzadfar, Farshad

AU - Larijani, Bagher

AU - Collaborators, GBD 2019 NAME Thyroid Cancer

AU - Moraga, Paula

N1 - KAUST Repository Item: Exported on 2022-12-15 Acknowledgements: The Bill and Melinda Gates Foundation, who were not involved in any way in the preparation of this manuscript, funded the GBD study. We would like to thank the Institute for Health Metrics and Evaluation staff and its collaborators who prepared these publicly available data. Z Piracha and U Saeed would like to acknowledge the support of the International Center of Medical Sciences Research, Islamabad (44000), Pakistan. A M Samy acknowledges the support from the Egyptian Fulbright Mission Program and being a member of the Egyptian Young Academy of Sciences.

PY - 2022/9/23

Y1 - 2022/9/23

N2 - Background: Thyroid cancer is the leading cause of mortality and morbidity among cancers of the endocrine system. We aimed to describe the trends of thyroid cancer burden in North Africa and Middle East for 1990–2019. Methods: Data on burden of thyroid cancer in North Africa and Middle East from 1990 to 2019 were obtained from the Global Burden of Disease (GBD) Study 2019. Decomposition analysis was used to estimate the effects of population growth, aging, and change in incident numbers on overall change of thyroid cancer incidence. Also, we used the comparative risk assessment framework of GBD to determine the burden of thyroid cancer attributable to a high body mass index (BMI). Results: In 2019, the age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) of thyroid cancer were 3.5 (2.9–4) and 0.5 (0.5–0.7) per 100,000, respectively. The highest age-standardized incidence, deaths, and disability-adjusted life year (DALY) rate were in Lebanon, Afghanistan, and United Arab Emirates, respectively. The ASIR of thyroid cancer in region was about 2.5 times higher among women, which had a positive association with increasing age. In 2019, the age-standardized deaths attributable to a high BMI was 16.7% of all deaths due to thyroid cancer. In 1990–2019, the overall change in thyroid cancer incident cases was a 396% increase which was mostly driven by the increase in disease-specific incidence rate (256.8%). Conclusions: Women, the elderly above about 60 years old, and countries with a higher sociodemographic index showed higher incidence rates of thyroid cancer. Regarding our findings, it is recommended to establish preventive plans by modification in life style like weight reduction programs.

AB - Background: Thyroid cancer is the leading cause of mortality and morbidity among cancers of the endocrine system. We aimed to describe the trends of thyroid cancer burden in North Africa and Middle East for 1990–2019. Methods: Data on burden of thyroid cancer in North Africa and Middle East from 1990 to 2019 were obtained from the Global Burden of Disease (GBD) Study 2019. Decomposition analysis was used to estimate the effects of population growth, aging, and change in incident numbers on overall change of thyroid cancer incidence. Also, we used the comparative risk assessment framework of GBD to determine the burden of thyroid cancer attributable to a high body mass index (BMI). Results: In 2019, the age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) of thyroid cancer were 3.5 (2.9–4) and 0.5 (0.5–0.7) per 100,000, respectively. The highest age-standardized incidence, deaths, and disability-adjusted life year (DALY) rate were in Lebanon, Afghanistan, and United Arab Emirates, respectively. The ASIR of thyroid cancer in region was about 2.5 times higher among women, which had a positive association with increasing age. In 2019, the age-standardized deaths attributable to a high BMI was 16.7% of all deaths due to thyroid cancer. In 1990–2019, the overall change in thyroid cancer incident cases was a 396% increase which was mostly driven by the increase in disease-specific incidence rate (256.8%). Conclusions: Women, the elderly above about 60 years old, and countries with a higher sociodemographic index showed higher incidence rates of thyroid cancer. Regarding our findings, it is recommended to establish preventive plans by modification in life style like weight reduction programs.

UR - http://hdl.handle.net/10754/686421

UR - https://www.frontiersin.org/articles/10.3389/fonc.2022.955358/full

U2 - 10.3389/fonc.2022.955358

DO - 10.3389/fonc.2022.955358

M3 - Article

C2 - 36212501

SN - 2234-943X

VL - 12

JO - Frontiers in Oncology

JF - Frontiers in Oncology

ER -

Burden of thyroid cancer in North Africa and Middle East 1990–2019

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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