Abstract
The synthesis of alkyne- and alkene-decorated lactams has been achieved through a photoredox-initiated radical cascade reaction. The developed Brønsted base assisted, photoredox-catalyzed, intramolecular 5-exo-trig cyclization/intermolecular radical addition/elimination reaction provides facile access to functionalized γ-lactams, with good functional group tolerance and high yields.
Original language | English (US) |
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Pages (from-to) | 14054-14058 |
Number of pages | 5 |
Journal | Chemistry - A European Journal |
Volume | 24 |
Issue number | 53 |
DOIs | |
State | Published - Aug 27 2018 |
Bibliographical note
KAUST Repository Item: Exported on 2020-04-23Acknowledgements: Y.A.H. would like to thank Deutscher Akademischer Austauschdienst (DAAD) for a doctoral scholarship. The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Programme (FP/2007–2013)/ERC Grant Agreement no. 617044 (SunCatChem).