A highly diastereoselective methodology for the efficient synthesis of functionalized indolo[2,3-a]quinolizidine skeletons in a one-pot operation has been developed. The protocol makes use of simple and inexpensive starting materials such as tryptamines, 1,3-dicarbonyl compounds and α,β- unsaturated aldehydes in the presence of a Brønsted acid catalyst.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Aug 7 2011|
ASJC Scopus subject areas
- Chemical Engineering(all)