Brønsted-acid catalyzed condensation-Michael reaction-Pictet- Spengler cyclization - Highly stereoselective synthesis of indoloquinolizidines

Magnus Rueping*, Chandra M.R. Volla

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

A highly diastereoselective methodology for the efficient synthesis of functionalized indolo[2,3-a]quinolizidine skeletons in a one-pot operation has been developed. The protocol makes use of simple and inexpensive starting materials such as tryptamines, 1,3-dicarbonyl compounds and α,β- unsaturated aldehydes in the presence of a Brønsted acid catalyst.

Original languageEnglish (US)
Pages (from-to)79-82
Number of pages4
JournalRSC ADVANCES
Volume1
Issue number1
DOIs
StatePublished - Aug 7 2011
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering

Fingerprint

Dive into the research topics of 'Brønsted-acid catalyzed condensation-Michael reaction-Pictet- Spengler cyclization - Highly stereoselective synthesis of indoloquinolizidines'. Together they form a unique fingerprint.

Cite this