Noura Raddadi, Ameur Cherif, Daniele Daffonchio

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Bacteria in the genus Bacillus are gram-positive, spore formers, and rod-shaped. They are very diverse in terms of physiology, ecological niche, genes sequences, and regulation. Their impact on human activity varies from probiotic effect1, 2 to severe pathogenecity. The oldest, most infectious, and potentially lethal human disease is the anthrax that is caused by Bacillus anthracis.3 However, many other species within this genus have emerged as new human pathogens associated with foodborne diseases that can cause severe and even fatal infections. These include B. Cereus, B. Weihenstephanenesis, B. Pumilus, B. Mojavensis, B. Licheniformis, B. Subtilis, and B. Circulans. All Bacillus species, due to endospore formation, can survive heat treatment and disinfection procedures and hence pose serious health concerns as contaminants of food or in hospital settings as a cause of nosocomial infections, 4–10 as well as severe illnesses, especially in immunocompromised patients or immunocompetent individuals with risk factors such as intravenous drug use, hemodialysis, and leukemia. The production of toxins and enzymes by these bacteria is considered the causative agent of several human diseases.

Original languageEnglish (US)
Title of host publicationMolecular Detection of Human Bacterial Pathogens
PublisherCRC Press
Number of pages11
ISBN (Electronic)9781439812396
ISBN (Print)9781439812389
StatePublished - Jan 1 2011

Bibliographical note

Publisher Copyright:
© 2011 by Taylor & Francis Group, LLC.

ASJC Scopus subject areas

  • General Medicine
  • General Engineering
  • General Agricultural and Biological Sciences
  • General Immunology and Microbiology


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