In contrast to animals, little is known about pattern formation in plants. Physiological and genetic data suggest the involvement of the phytohormone auxin in this process. Here, we characterize a novel member of the PIN family of putative auxin efflux carriers, Arabidopsis PIN4, that is localized in developing and mature root meristems. Atpin4 mutants are defective in establishment and maintenance of endogenous auxin gradients, fail to canalize externally applied auxin, and display various patterning defects in both embryonic and seedling roots. We propose a role for AtPIN4 in generating a sink for auxin below the quiescent center of the root meristem that is essential for auxin distribution and patterning.
|Original language||English (US)|
|Number of pages||13|
|State||Published - Mar 8 2002|
Bibliographical noteFunding Information:
We thank Petra Tänzler, Michaela Lehnen, and Thomas Steinmann for technical help. We acknowledge the Arabidopsis Biological Resource Center (Columbus, OH) and Thomas Altman for providing material. We also gratefully acknowledge the ADIS service group for DNA sequencing and ZIGIA (Center for Functional Genomics in Arabidopsis) for the En lines. We are grateful to our colleagues, particularly Leo Gälweiler, Niko Geldner, Matthias Godde, and Kathrin Schrick for critical reading of the manuscript. This work was supported by a fellowship of the Deutscher Akademischer Austauschdienset (J.F.), the Deutsche Forschungsgemeinschaft (Schwerpunktprogramm Phytohormone), the European Communities Biotechnology Programs, the Fonds der Chemischen Industrie, and the INCO-Copernicus Program.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)