(Chemical Equation Presented) An addition-cyclization reaction cascade triggeredby an organocatalyst was used for the enantioselective preparation of a series of biologically active 1,2- and 1,4-pyranonaphthoquinones from aliphatic andaromatic α,β-unsaturated aldehydes and2-hydroxy-1-4- naphthoquinone. A trimethylsilyl-protected diarylprolinol serves as the Lewis base organocatalyst.
|Original language||English (US)|
|Number of pages||4|
|Journal||Angewandte Chemie - International Edition|
|State||Published - Apr 7 2008|
- Iminium ions
- Lewis base catalysis
ASJC Scopus subject areas