Asymmetric H-D exchange reactions of fluorinated aromatic ketones

Yujun Zhao; XiaoZhi Lim; Yuanhang Pan; Lili Zong; Wei Feng; Choonhong Tan; Kuo-Wei Huang

doi:10.1039/c2cc31443f

Asymmetric H-D exchange reactions of fluorinated aromatic ketones

Yujun Zhao, XiaoZhi Lim, Yuanhang Pan, Lili Zong, Wei Feng, Choonhong Tan, Kuo-Wei Huang

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Chiral bicyclic guanidine catalyzes the asymmetric H-D exchange reactions. Up to 30% ee was achieved. DFT calculations were employed to elucidate and explain the origin of the reaction's stereoselectivity. © 2012 The Royal Society of Chemistry.

Original language	English (US)
Pages (from-to)	5479
Journal	Chemical Communications
Volume	48
Issue number	44
DOIs	https://doi.org/10.1039/c2cc31443f
State	Published - 2012

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We wish to thank the National University of Singapore and King Abdullah University of Science and Technology for their generous financial support.

ASJC Scopus subject areas

Materials Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Ceramics and Composites
General Chemistry
Catalysis
Electronic, Optical and Magnetic Materials

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title = "Asymmetric H-D exchange reactions of fluorinated aromatic ketones",

abstract = "Chiral bicyclic guanidine catalyzes the asymmetric H-D exchange reactions. Up to 30% ee was achieved. DFT calculations were employed to elucidate and explain the origin of the reaction's stereoselectivity. {\textcopyright} 2012 The Royal Society of Chemistry.",

author = "Yujun Zhao and XiaoZhi Lim and Yuanhang Pan and Lili Zong and Wei Feng and Choonhong Tan and Kuo-Wei Huang",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We wish to thank the National University of Singapore and King Abdullah University of Science and Technology for their generous financial support.",

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T1 - Asymmetric H-D exchange reactions of fluorinated aromatic ketones

AU - Zhao, Yujun

AU - Lim, XiaoZhi

AU - Pan, Yuanhang

AU - Zong, Lili

AU - Feng, Wei

AU - Tan, Choonhong

AU - Huang, Kuo-Wei

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We wish to thank the National University of Singapore and King Abdullah University of Science and Technology for their generous financial support.

PY - 2012

Y1 - 2012

N2 - Chiral bicyclic guanidine catalyzes the asymmetric H-D exchange reactions. Up to 30% ee was achieved. DFT calculations were employed to elucidate and explain the origin of the reaction's stereoselectivity. © 2012 The Royal Society of Chemistry.

AB - Chiral bicyclic guanidine catalyzes the asymmetric H-D exchange reactions. Up to 30% ee was achieved. DFT calculations were employed to elucidate and explain the origin of the reaction's stereoselectivity. © 2012 The Royal Society of Chemistry.

UR - http://hdl.handle.net/10754/561983

UR - http://xlink.rsc.org/?DOI=c2cc31443f

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U2 - 10.1039/c2cc31443f

DO - 10.1039/c2cc31443f

M3 - Article

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VL - 48

SP - 5479

JO - Chemical Communications

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ER -

Asymmetric H-D exchange reactions of fluorinated aromatic ketones

Abstract

Bibliographical note

ASJC Scopus subject areas

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