Asymmetric H-D exchange reactions of fluorinated aromatic ketones

Yujun Zhao, XiaoZhi Lim, Yuanhang Pan, Lili Zong, Wei Feng, Choonhong Tan, Kuo-Wei Huang

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Chiral bicyclic guanidine catalyzes the asymmetric H-D exchange reactions. Up to 30% ee was achieved. DFT calculations were employed to elucidate and explain the origin of the reaction's stereoselectivity. © 2012 The Royal Society of Chemistry.
Original languageEnglish (US)
Pages (from-to)5479
JournalChemical Communications
Issue number44
StatePublished - 2012

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We wish to thank the National University of Singapore and King Abdullah University of Science and Technology for their generous financial support.

ASJC Scopus subject areas

  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Ceramics and Composites
  • Chemistry(all)
  • Catalysis
  • Electronic, Optical and Magnetic Materials


Dive into the research topics of 'Asymmetric H-D exchange reactions of fluorinated aromatic ketones'. Together they form a unique fingerprint.

Cite this