Chiral bicyclic guanidine catalyzes the asymmetric H-D exchange reactions. Up to 30% ee was achieved. DFT calculations were employed to elucidate and explain the origin of the reaction's stereoselectivity. © 2012 The Royal Society of Chemistry.
Bibliographical noteKAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We wish to thank the National University of Singapore and King Abdullah University of Science and Technology for their generous financial support.
ASJC Scopus subject areas
- Materials Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Ceramics and Composites
- Electronic, Optical and Magnetic Materials