Archaea from the gut microbiota of humans: Could be linked to chronic diseases?

Denise Mafra; Marcia Ribeiro; Larissa Fonseca; Bruna Regis; Ludmila F M F Cardozo; Henrique Fragoso Dos Santos; Hugo Emiliano de Jesus; Junia Schultz; Paul G Shiels; Peter Stenvinkel; Alexandre S. Rosado

doi:10.1016/j.anaerobe.2022.102629

Archaea from the gut microbiota of humans: Could be linked to chronic diseases?

Denise Mafra, Marcia Ribeiro, Larissa Fonseca, Bruna Regis, Ludmila F M F Cardozo, Henrique Fragoso Dos Santos, Hugo Emiliano de Jesus, Junia Schultz, Paul G Shiels, Peter Stenvinkel, Alexandre S. Rosado

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Archaea comprise a unique domain of organisms with distinct biochemical and genetic differences from bacteria. Methane-forming archaea, methanogens, constitute the predominant group of archaea in the human gut microbiota, with Methanobrevibacter smithii being the most prevalent. However, the effect of methanogenic archaea and their methane production on chronic disease remains controversial. As perturbation of the microbiota is a feature of chronic conditions, such as cardiovascular disease, neurodegenerative diseases and chronic kidney disease, assessing the influence of archaea could provide a new clue to mitigating adverse effects associated with dysbiosis. In this review, we will discuss the putative role of archaea in the gut microbiota in humans and the possible link to chronic diseases.

Original language	English (US)
Pages (from-to)	102629
Journal	Anaerobe
DOIs	https://doi.org/10.1016/j.anaerobe.2022.102629
State	Published - Aug 17 2022

Bibliographical note

KAUST Repository Item: Exported on 2022-09-14
Acknowledged KAUST grant number(s): BAS/1/1096-01-01
Acknowledgements: Conselho Nacional de Pesquisa (CNPq) and Coordenação de Aperfeiçoamento de Pessoal deNível Superior (CAPES), Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) support Denise Mafra research. ASR and JS were supported by KAUST grant KAUST (BAS/1/1096-01-01).

ASJC Scopus subject areas

Infectious Diseases
Microbiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.anaerobe.2022.102629

https://repository.kaust.edu.sa/bitstream/10754/680474/1/1-s2.0-S1075996422001226-main_removed.pdf

Cite this

@article{9e57909df5e449429f873855d29e0b11,

title = "Archaea from the gut microbiota of humans: Could be linked to chronic diseases?",

abstract = "Archaea comprise a unique domain of organisms with distinct biochemical and genetic differences from bacteria. Methane-forming archaea, methanogens, constitute the predominant group of archaea in the human gut microbiota, with Methanobrevibacter smithii being the most prevalent. However, the effect of methanogenic archaea and their methane production on chronic disease remains controversial. As perturbation of the microbiota is a feature of chronic conditions, such as cardiovascular disease, neurodegenerative diseases and chronic kidney disease, assessing the influence of archaea could provide a new clue to mitigating adverse effects associated with dysbiosis. In this review, we will discuss the putative role of archaea in the gut microbiota in humans and the possible link to chronic diseases.",

author = "Denise Mafra and Marcia Ribeiro and Larissa Fonseca and Bruna Regis and Cardozo, {Ludmila F M F} and {Fragoso Dos Santos}, Henrique and {Emiliano de Jesus}, Hugo and Junia Schultz and Shiels, {Paul G} and Peter Stenvinkel and Rosado, {Alexandre S.}",

note = "KAUST Repository Item: Exported on 2022-09-14 Acknowledged KAUST grant number(s): BAS/1/1096-01-01 Acknowledgements: Conselho Nacional de Pesquisa (CNPq) and Coordena{\c c}{\~a}o de Aperfei{\c c}oamento de Pessoal deN{\'i}vel Superior (CAPES), Funda{\c c}{\~a}o de Amparo {\`a} Pesquisa do Estado do Rio de Janeiro (FAPERJ) support Denise Mafra research. ASR and JS were supported by KAUST grant KAUST (BAS/1/1096-01-01).",

year = "2022",

month = aug,

day = "17",

doi = "10.1016/j.anaerobe.2022.102629",

language = "English (US)",

pages = "102629",

journal = "Anaerobe",