Arabidopsis MAPKKK18 positively regulates drought stress resistance via downstream MAPKK3

Yuanyuan Li; Huixian Cai; Pu Liu; Chunyan Wang; Huiyang Gao; Changai Wu; Kang Yan; Shizhong Zhang; Jinguang Huang; Chengchao Zheng

doi:10.1016/j.bbrc.2017.01.104

Arabidopsis MAPKKK18 positively regulates drought stress resistance via downstream MAPKK3

Yuanyuan Li, Huixian Cai, Pu Liu, Chunyan Wang, Huiyang Gao, Changai Wu, Kang Yan, Shizhong Zhang, Jinguang Huang, Chengchao Zheng

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

Mitogen-activated protein kinase (MAPK) cascades are conserved and vital signaling components in the responses to various ambient stresses. Here, we report the identification of MAPKKK18, a drought resistance associated MAPK kinase kinase in Arabidopsis. The mapkkk18 knockout mutants displayed hypersensitivity to drought stress, whereas overaccumulation of MAPKKK18 in transgenic Arabidopsis plants significantly enhanced the resistance to drought. Expression pattern analysis revealed that the inducible expression of MAPKKK18 by osmotic stress was ABA and the canonical ABA signaling pathway dependent. Furthermore, MAPKKK18 mainly exerted its regulatory roles via downstream MAPKK3. These findings uncovered important roles for MAPKKK18 in drought resistance and expanded our understanding of the MAPK pathways in modulating abiotic stress responses.

Original language	English (US)
Pages (from-to)	292-297
Number of pages	6
Journal	Biochemical and Biophysical Research Communications
Volume	484
Issue number	2
DOIs	https://doi.org/10.1016/j.bbrc.2017.01.104
State	Published - Feb 16 2017
Externally published	Yes

Bibliographical note

KAUST Repository Item: Exported on 2022-06-03
Acknowledgements: We thank Dr. Heribert Hirt (Center for Desert Agriculture, King Abdullah University of Science and Technology) for kindly providing us the MAPKKK18pro
This publication acknowledges KAUST support, but has no KAUST affiliated authors.

ASJC Scopus subject areas

Biochemistry
Cell Biology
Molecular Biology
Biophysics

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10.1016/j.bbrc.2017.01.104

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@article{bb29e618818048d89e7dba64f4b49342,

title = "Arabidopsis MAPKKK18 positively regulates drought stress resistance via downstream MAPKK3",

abstract = "Mitogen-activated protein kinase (MAPK) cascades are conserved and vital signaling components in the responses to various ambient stresses. Here, we report the identification of MAPKKK18, a drought resistance associated MAPK kinase kinase in Arabidopsis. The mapkkk18 knockout mutants displayed hypersensitivity to drought stress, whereas overaccumulation of MAPKKK18 in transgenic Arabidopsis plants significantly enhanced the resistance to drought. Expression pattern analysis revealed that the inducible expression of MAPKKK18 by osmotic stress was ABA and the canonical ABA signaling pathway dependent. Furthermore, MAPKKK18 mainly exerted its regulatory roles via downstream MAPKK3. These findings uncovered important roles for MAPKKK18 in drought resistance and expanded our understanding of the MAPK pathways in modulating abiotic stress responses.",

author = "Yuanyuan Li and Huixian Cai and Pu Liu and Chunyan Wang and Huiyang Gao and Changai Wu and Kang Yan and Shizhong Zhang and Jinguang Huang and Chengchao Zheng",

note = "KAUST Repository Item: Exported on 2022-06-03 Acknowledgements: We thank Dr. Heribert Hirt (Center for Desert Agriculture, King Abdullah University of Science and Technology) for kindly providing us the MAPKKK18pro This publication acknowledges KAUST support, but has no KAUST affiliated authors.",

year = "2017",

month = feb,

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doi = "10.1016/j.bbrc.2017.01.104",

language = "English (US)",

volume = "484",

pages = "292--297",

journal = "Biochemical and Biophysical Research Communications",

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TY - JOUR

T1 - Arabidopsis MAPKKK18 positively regulates drought stress resistance via downstream MAPKK3

AU - Li, Yuanyuan

AU - Cai, Huixian

AU - Liu, Pu

AU - Wang, Chunyan

AU - Gao, Huiyang

AU - Wu, Changai

AU - Yan, Kang

AU - Zhang, Shizhong

AU - Huang, Jinguang

AU - Zheng, Chengchao

N1 - KAUST Repository Item: Exported on 2022-06-03 Acknowledgements: We thank Dr. Heribert Hirt (Center for Desert Agriculture, King Abdullah University of Science and Technology) for kindly providing us the MAPKKK18pro This publication acknowledges KAUST support, but has no KAUST affiliated authors.

PY - 2017/2/16

Y1 - 2017/2/16

N2 - Mitogen-activated protein kinase (MAPK) cascades are conserved and vital signaling components in the responses to various ambient stresses. Here, we report the identification of MAPKKK18, a drought resistance associated MAPK kinase kinase in Arabidopsis. The mapkkk18 knockout mutants displayed hypersensitivity to drought stress, whereas overaccumulation of MAPKKK18 in transgenic Arabidopsis plants significantly enhanced the resistance to drought. Expression pattern analysis revealed that the inducible expression of MAPKKK18 by osmotic stress was ABA and the canonical ABA signaling pathway dependent. Furthermore, MAPKKK18 mainly exerted its regulatory roles via downstream MAPKK3. These findings uncovered important roles for MAPKKK18 in drought resistance and expanded our understanding of the MAPK pathways in modulating abiotic stress responses.

AB - Mitogen-activated protein kinase (MAPK) cascades are conserved and vital signaling components in the responses to various ambient stresses. Here, we report the identification of MAPKKK18, a drought resistance associated MAPK kinase kinase in Arabidopsis. The mapkkk18 knockout mutants displayed hypersensitivity to drought stress, whereas overaccumulation of MAPKKK18 in transgenic Arabidopsis plants significantly enhanced the resistance to drought. Expression pattern analysis revealed that the inducible expression of MAPKKK18 by osmotic stress was ABA and the canonical ABA signaling pathway dependent. Furthermore, MAPKKK18 mainly exerted its regulatory roles via downstream MAPKK3. These findings uncovered important roles for MAPKKK18 in drought resistance and expanded our understanding of the MAPK pathways in modulating abiotic stress responses.

UR - http://hdl.handle.net/10754/678502

UR - https://linkinghub.elsevier.com/retrieve/pii/S0006291X17301638

UR - http://www.scopus.com/inward/record.url?scp=85010987098&partnerID=8YFLogxK

U2 - 10.1016/j.bbrc.2017.01.104

DO - 10.1016/j.bbrc.2017.01.104

M3 - Article

SN - 1090-2104

VL - 484

SP - 292

EP - 297

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 2

ER -

Arabidopsis MAPKKK18 positively regulates drought stress resistance via downstream MAPKK3

Abstract

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