Applying ontology design patterns to the implementation of relations in GENIA

Robert Hoehndorf*, Axel Cyrille Ngonga Ngomo, Sampo Pyysalo, Tomoko Ohta, Anika Oellrich, Dietrich Rebholz-Schuhmann

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


Motivation: Annotated reference corpora such as the GENIA corpus play an important role in biomedical information extraction. A semantic annotation of the natural language texts in these reference corpora using formal ontologies and logic is challenging due to the ambiguous use of natural language and natural language semantics. Providing formal definitions and axioms for these relations would offer the means for developing consistent and verifiable annotation guidelines and allow for the automatic verification of annotations as well as enabling the discovery of new information through deductive inferences. Results: We developed a formal ontology of relations based on the relations used in the recent GENIA corpus annotations. For this purpose, we selected existing axiom systems based on the desired properties of the relations within the domain and provided new axioms for several relations. To apply this ontology of relations to the semantic annotation of natural language texts, we developed and implemented two ontology design patterns. We provide an implementation of the ontology of relations in the Web Ontology Language (OWL). By combining the implementation of the design patterns and that of the relation ontology, we also provide a software application to convert annotated GENIA abstracts into OWL ontologies. In this way, we make these ontologies amenable for automated verification, deductive inferences and other knowledge-based applications.

Original languageEnglish (US)
Pages (from-to)27-35
Number of pages9
JournalCEUR Workshop Proceedings
StatePublished - 2010
Externally publishedYes
Event4th International Symposium on Semantic Mining in Biomedicine, SMBM 2010 - Cambridge, United Kingdom
Duration: Oct 25 2010Oct 26 2010

ASJC Scopus subject areas

  • General Computer Science


Dive into the research topics of 'Applying ontology design patterns to the implementation of relations in GENIA'. Together they form a unique fingerprint.

Cite this