An answer in the palm of your hand: Microfluidics for analytical applications

Yolanda Fintschenko; Wen Yee Choi; Eric B. Cummings; Jean M.J. Fréchet; Julia A. Fruetel; Emily F. Hilder; Dieudonne A. Mair; Timothy J. Shepodd; Frantisek Svec

doi:10.1117/12.480775

An answer in the palm of your hand: Microfluidics for analytical applications

Yolanda Fintschenko^*, Wen Yee Choi, Eric B. Cummings, Jean M.J. Fréchet, Julia A. Fruetel, Emily F. Hilder, Dieudonne A. Mair, Timothy J. Shepodd, Frantisek Svec

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

4 Scopus citations

Abstract

We have applied CZE and CEC in microfluidic devices to a number of analytical problems including the analysis of chemical warfare agents, polycyclic aromatic hydrocarbons, and proteins. In addition to developments in the areas of separations, we are also heavily involved in the "front-end" of analytical systems particularly in the area of sample preconcentration. We have a particular interest in the concentration of a wide range of molecules including small molecules, biopolymers, and cells. Our current toolbox includes a microfluidic platform known as Liquid Phase μChemLab™ developed by a team at Sandia for protein analysis. This platform has been demonstrated with protein biotoxins, CW agent degradation products, protein preconcentration, and is suitable for other targets. Additionally, electrodeless dielectrophoresis technology developed at Sandia is an attractive alternative to filters for cell concentration.

Original language	English (US)
Pages (from-to)	196-207
Number of pages	12
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	4982
DOIs	https://doi.org/10.1117/12.480775
State	Published - 2003
Externally published	Yes
Event	Microfluidics, BioMEMS, and Medical Microsystems - San Jose, CA, United States Duration: Jan 27 2003 → Jan 29 2003

Keywords

CEC
CZE
Dielectrophoresis
Microfluidics
Platform
Porous polymer monolith
Preconcentrator
μChemLab™

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.480775

Cite this

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title = "An answer in the palm of your hand: Microfluidics for analytical applications",

abstract = "We have applied CZE and CEC in microfluidic devices to a number of analytical problems including the analysis of chemical warfare agents, polycyclic aromatic hydrocarbons, and proteins. In addition to developments in the areas of separations, we are also heavily involved in the {"}front-end{"} of analytical systems particularly in the area of sample preconcentration. We have a particular interest in the concentration of a wide range of molecules including small molecules, biopolymers, and cells. Our current toolbox includes a microfluidic platform known as Liquid Phase μChemLab{\texttrademark} developed by a team at Sandia for protein analysis. This platform has been demonstrated with protein biotoxins, CW agent degradation products, protein preconcentration, and is suitable for other targets. Additionally, electrodeless dielectrophoresis technology developed at Sandia is an attractive alternative to filters for cell concentration.",

keywords = "CEC, CZE, Dielectrophoresis, Microfluidics, Platform, Porous polymer monolith, Preconcentrator, μChemLab{\texttrademark}",

author = "Yolanda Fintschenko and Choi, {Wen Yee} and Cummings, {Eric B.} and Fr{\'e}chet, {Jean M.J.} and Fruetel, {Julia A.} and Hilder, {Emily F.} and Mair, {Dieudonne A.} and Shepodd, {Timothy J.} and Frantisek Svec",

year = "2003",

doi = "10.1117/12.480775",

language = "English (US)",

volume = "4982",

pages = "196--207",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Microfluidics, BioMEMS, and Medical Microsystems ; Conference date: 27-01-2003 Through 29-01-2003",

}

TY - JOUR

T1 - An answer in the palm of your hand

T2 - Microfluidics, BioMEMS, and Medical Microsystems

AU - Fintschenko, Yolanda

AU - Choi, Wen Yee

AU - Cummings, Eric B.

AU - Fréchet, Jean M.J.

AU - Fruetel, Julia A.

AU - Hilder, Emily F.

AU - Mair, Dieudonne A.

AU - Shepodd, Timothy J.

AU - Svec, Frantisek

PY - 2003

Y1 - 2003

N2 - We have applied CZE and CEC in microfluidic devices to a number of analytical problems including the analysis of chemical warfare agents, polycyclic aromatic hydrocarbons, and proteins. In addition to developments in the areas of separations, we are also heavily involved in the "front-end" of analytical systems particularly in the area of sample preconcentration. We have a particular interest in the concentration of a wide range of molecules including small molecules, biopolymers, and cells. Our current toolbox includes a microfluidic platform known as Liquid Phase μChemLab™ developed by a team at Sandia for protein analysis. This platform has been demonstrated with protein biotoxins, CW agent degradation products, protein preconcentration, and is suitable for other targets. Additionally, electrodeless dielectrophoresis technology developed at Sandia is an attractive alternative to filters for cell concentration.

AB - We have applied CZE and CEC in microfluidic devices to a number of analytical problems including the analysis of chemical warfare agents, polycyclic aromatic hydrocarbons, and proteins. In addition to developments in the areas of separations, we are also heavily involved in the "front-end" of analytical systems particularly in the area of sample preconcentration. We have a particular interest in the concentration of a wide range of molecules including small molecules, biopolymers, and cells. Our current toolbox includes a microfluidic platform known as Liquid Phase μChemLab™ developed by a team at Sandia for protein analysis. This platform has been demonstrated with protein biotoxins, CW agent degradation products, protein preconcentration, and is suitable for other targets. Additionally, electrodeless dielectrophoresis technology developed at Sandia is an attractive alternative to filters for cell concentration.

KW - CEC

KW - CZE

KW - Dielectrophoresis

KW - Microfluidics

KW - Platform

KW - Porous polymer monolith

KW - Preconcentrator

KW - μChemLab™

UR - http://www.scopus.com/inward/record.url?scp=0037721587&partnerID=8YFLogxK

U2 - 10.1117/12.480775

DO - 10.1117/12.480775

M3 - Conference article

AN - SCOPUS:0037721587

SN - 0277-786X

VL - 4982

SP - 196

EP - 207

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

Y2 - 27 January 2003 through 29 January 2003

ER -

An answer in the palm of your hand: Microfluidics for analytical applications

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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