Ambipolar inverters based on cofacial vertical organic electrochemical transistor pairs for biosignal amplification

Reem B. Rashid, weiyuan du, Sophie Griggs, Iuliana P. Maria, Iain McCulloch, Jonathan Rivnay

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


On-site signal amplification for bioelectronic sensing is a desirable approach to improving recorded signal quality and to reducing the burden on signal transmission and back-end electronics. While organic electrochemical transistors (OECTs) have been used as local transducers of bioelectronic signals, their current output presents challenges for implementation. OECT-based circuits offer new opportunities for high-performance signal processing. In this work, we introduce an active sensing node based on cofacial vertical OECTs forming an ambipolar complementary inverter. The inverter, which shows a voltage gain of 28, is composed of two OECTs on opposite side walls of a single active area, resulting in a footprint identical to a planar OECT. The inverter is used as an analog voltage preamplifier for recording electrocardiogram signals when biased at the input voltage corresponding to peak gain. We further demonstrate compatibility with nontraditional fabrication methods with potential benefits for rapid prototyping and large-area printed electronics.
Original languageEnglish (US)
JournalScience advances
Issue number37
StatePublished - Sep 8 2021

Bibliographical note

KAUST Repository Item: Exported on 2021-09-10
Acknowledged KAUST grant number(s): OSR-2018-CARF/CCF-3079, OSR- 2019-CRG8-4086
Acknowledgements: We acknowledge financial support from King Abdullah University of Science and Technology Office of Sponsored Research (OSR) under awards nos. OSR-2018-CARF/CCF-3079 and OSR- 2019-CRG8-4086. This work used Northwestern University Micro/Nano Fabrication Facility (NUFAB), which is partially supported by Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), the Materials Research Science and Engineering Centers (MRSEC; DMR-1720139), the State of Illinois, and Northwestern University. This work made use of the Keck-II and EPIC facilities of Northwestern University’s NUANCE Center, which has received support from the SHyNE Resource (NSF ECCS-1542205); the MRSEC program (NSF DMR-1720139) at the Materials Research Center; the International Institute for Nanotechnology (IIN); the Keck Foundation; and the State of Illinois, through the IIN


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