TY - JOUR
T1 - A vision and strategy for the virtual physiological human in 2010 and beyond
AU - Hunter, Peter
AU - Coveney, Peter V.
AU - De Bono, Bernard
AU - Diaz, Vanessa
AU - Fenner, John
AU - Frangi, Alejandro F.
AU - Harris, Peter
AU - Hose, Rod
AU - Kohl, Peter
AU - Lawford, Pat
AU - McCormack, Keith
AU - Mendes, Miriam
AU - Omholt, Stig
AU - Quarteroni, Alfio
AU - Skår, John
AU - Tegner, Jesper
AU - Thomas, S. Randall
AU - Tollis, Ioannis
AU - Tsamardinos, Ioannis
AU - Van Beek, Johannes H.G.M.
AU - Viceconti, Marco
PY - 2010/6/13
Y1 - 2010/6/13
N2 - European funding under framework 7 (FP7) for the virtual physiological human (VPH) project has been in place now for nearly 2 years. The VPH network of excellence (NoE) is helping in the development of common standards, open-source software, freely accessible data and model repositories, and various training and dissemination activities for the project. It is also helping to coordinate the many clinically targeted projects that have been funded under the FP7 calls. An initial vision for the VPH was defined by framework 6 strategy for a European physiome (STEP) project in 2006. It is now time to assess the accomplishments of the last 2 years and update the STEP vision for the VPH. We consider the biomedical science, healthcare and information and communications technology challenges facing the project and we propose the VPH Institute as a means of sustaining the vision of VPH beyond the time frame of the NoE.
AB - European funding under framework 7 (FP7) for the virtual physiological human (VPH) project has been in place now for nearly 2 years. The VPH network of excellence (NoE) is helping in the development of common standards, open-source software, freely accessible data and model repositories, and various training and dissemination activities for the project. It is also helping to coordinate the many clinically targeted projects that have been funded under the FP7 calls. An initial vision for the VPH was defined by framework 6 strategy for a European physiome (STEP) project in 2006. It is now time to assess the accomplishments of the last 2 years and update the STEP vision for the VPH. We consider the biomedical science, healthcare and information and communications technology challenges facing the project and we propose the VPH Institute as a means of sustaining the vision of VPH beyond the time frame of the NoE.
KW - Computational physiology
KW - Multi-scale modelling
KW - Physiome
KW - Virtual physiological human
UR - http://www.scopus.com/inward/record.url?scp=77953529580&partnerID=8YFLogxK
U2 - 10.1098/rsta.2010.0048
DO - 10.1098/rsta.2010.0048
M3 - Article
C2 - 20439264
AN - SCOPUS:77953529580
SN - 1364-503X
VL - 368
SP - 2595
EP - 2614
JO - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
JF - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
IS - 1920
ER -
