A vision and strategy for the virtual physiological human in 2010 and beyond

Peter Hunter*, Peter V. Coveney, Bernard De Bono, Vanessa Diaz, John Fenner, Alejandro F. Frangi, Peter Harris, Rod Hose, Peter Kohl, Pat Lawford, Keith McCormack, Miriam Mendes, Stig Omholt, Alfio Quarteroni, John Skår, Jesper Tegner, S. Randall Thomas, Ioannis Tollis, Ioannis Tsamardinos, Johannes H.G.M. Van BeekMarco Viceconti

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

113 Scopus citations


European funding under framework 7 (FP7) for the virtual physiological human (VPH) project has been in place now for nearly 2 years. The VPH network of excellence (NoE) is helping in the development of common standards, open-source software, freely accessible data and model repositories, and various training and dissemination activities for the project. It is also helping to coordinate the many clinically targeted projects that have been funded under the FP7 calls. An initial vision for the VPH was defined by framework 6 strategy for a European physiome (STEP) project in 2006. It is now time to assess the accomplishments of the last 2 years and update the STEP vision for the VPH. We consider the biomedical science, healthcare and information and communications technology challenges facing the project and we propose the VPH Institute as a means of sustaining the vision of VPH beyond the time frame of the NoE.

Original languageEnglish (US)
Pages (from-to)2595-2614
Number of pages20
JournalPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Issue number1920
StatePublished - Jun 13 2010


  • Computational physiology
  • Multi-scale modelling
  • Physiome
  • Virtual physiological human

ASJC Scopus subject areas

  • Mathematics(all)
  • Engineering(all)
  • Physics and Astronomy(all)


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