1,3-Diaryl-2-propene-1-ones react with ethyl cyanoacetate in presence of sodium ethoxide at room temperature to give 2-aroyl-1,3,5-triaryl-4-carbethoxy-4-cyanocyclohexanols. The structure of the reaction products was established by infrared, H-1 and C-13 nuclear magnetic resonance spectral data as well as elemental analysis. X-ray crystallography shows the presence of the cyclohexanol moeity.
|Original language||English (US)|
|Number of pages||8|
|State||Published - Jan 1 1989|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry