In this work, a novel very wideband 4-element monopole based multiple-input multiple-output (MIMO) antenna system with single connected antenna array (CAA) is presented. The CAA is based on a single slot which is etched on the ground plane. A 2 × 1 power divider/combiner is used to excite the slot to act as a CAA. The proposed design covers the 4G bands between 1850 and 3700, and the 28 GHz 5G band. The covered bandwidths are 1462 and 240 MHz from 1843 to 3305 MHz and 3500 to 3740 MHz, respectively, for 4G applications. A bandwidth of 1.22 GHz from 27.5 to 28.72 GHz is obtained for 5G applications. The proposed antenna system is designed on a double layer RO4350B substrate with height of 0.76 mm and dielectric constant of 3.5. The total size of the design is 115 × 65 × 0.76 mm. It is compact, low profile and suitable for wireless handheld devices. The MIMO performance metrics such as isolation and ECC are evaluated and good agreement between simulations and measurements is achieved.