TY - JOUR
T1 - A novel synthesis of non-aggregated spinel nickel ferrite nanosheets for developing non-enzymatic reactive oxygen species sensor in biological samples
AU - Sakthivel, Kogularasu
AU - Mani, Govindasamy
AU - Chen, Shen Ming
AU - Lin, Shih Hao
AU - Muthumariappan, Akilarasan
AU - Mani, Veerappan
N1 - Generated from Scopus record by KAUST IRTS on 2023-09-21
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Herein, the synthesis of novel non-aggregated spinel nickel ferrite, NiFe2O4 nanosheets (NiFe2O4 NSs) and its application towards the selective electrocatalytic reduction of hydrogen peroxide are described. Initially, NiFe2O4 NSs is synthesized by one-step hydrothermal approach, and numerous characterizations deliberately explain the compound's composition and structure. Finally, the NiFe2O4 NSs underwent direct non-enzymatic electrochemistry and succeeded, it as mimicking Horseradish Peroxidase properties. The significance of non-aggregated NiFe2O4 NSs together with good electrocatalytic properties leads the material to the platform for electrochemical sensors. Moreover, NiFe2O4 NSs is fabricated and validated as an enzyme-free biosensor for the sensitive detection of H2O2. The demonstrated sensor revealed excellent detection of H2O2 with the pico-molar detection limit (12.4 pM), and also it offered good analytical parameters with more extensive linear range and higher sensitivity. Likewise, the non-enzymatic biosensor annexes good durability, reproducibility, and selectivity towards the determination of H2O2. Due to the nourishing capacity of the prepared NiFe2O4 NSs, it is employed for the enzyme-free detection of H2O2 in human blood and rat brain serum samples.
AB - Herein, the synthesis of novel non-aggregated spinel nickel ferrite, NiFe2O4 nanosheets (NiFe2O4 NSs) and its application towards the selective electrocatalytic reduction of hydrogen peroxide are described. Initially, NiFe2O4 NSs is synthesized by one-step hydrothermal approach, and numerous characterizations deliberately explain the compound's composition and structure. Finally, the NiFe2O4 NSs underwent direct non-enzymatic electrochemistry and succeeded, it as mimicking Horseradish Peroxidase properties. The significance of non-aggregated NiFe2O4 NSs together with good electrocatalytic properties leads the material to the platform for electrochemical sensors. Moreover, NiFe2O4 NSs is fabricated and validated as an enzyme-free biosensor for the sensitive detection of H2O2. The demonstrated sensor revealed excellent detection of H2O2 with the pico-molar detection limit (12.4 pM), and also it offered good analytical parameters with more extensive linear range and higher sensitivity. Likewise, the non-enzymatic biosensor annexes good durability, reproducibility, and selectivity towards the determination of H2O2. Due to the nourishing capacity of the prepared NiFe2O4 NSs, it is employed for the enzyme-free detection of H2O2 in human blood and rat brain serum samples.
UR - https://linkinghub.elsevier.com/retrieve/pii/S1572665718303187
UR - http://www.scopus.com/inward/record.url?scp=85046706380&partnerID=8YFLogxK
U2 - 10.1016/j.jelechem.2018.04.058
DO - 10.1016/j.jelechem.2018.04.058
M3 - Article
SN - 1572-6657
VL - 820
SP - 161
EP - 167
JO - Journal of Electroanalytical Chemistry
JF - Journal of Electroanalytical Chemistry
ER -