A Novel Poly(vinylidene fluoride)-Based 4-Miktoarm Star Terpolymer: Synthesis and Self-Assembly

Yogesh Raghunath Patil; Panagiotis Bilalis; George Polymeropoulos; Sarah Almahdali; Nikos Hadjichristidis; Valentin Rodionov

doi:10.1021/acs.molpharmaceut.8b00010

A Novel Poly(vinylidene fluoride)-Based 4-Miktoarm Star Terpolymer: Synthesis and Self-Assembly

Yogesh Raghunath Patil, Panagiotis Bilalis, George Polymeropoulos, Sarah Almahdali, Nikos Hadjichristidis, Valentin Rodionov

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

A well-defined amphiphilic miktoarm polymer incorporating poly(vinylidene fluoride) (PVDF), polystyrene (PS), and poly(ethylene glycol) (PEG) blocks was synthesized via a combination of atom-transfer radical polymerization (ATRP), iodine transfer radical polymerization (ITP), and copper-catalyzed azide-alkyne cycloaddition (CuAAC). Morphology and self-assembly of this star polymer were examined in organic solvents and in water. The aggregates formed in water were found to possess unusual frustrated topology due to immiscibility of PS and PVDF. The polymer was evaluated for transport of small hydrophobic molecules in water.

Original language	English (US)
Pages (from-to)	3005-3009
Number of pages	5
Journal	Molecular Pharmaceutics
Volume	15
Issue number	8
DOIs	https://doi.org/10.1021/acs.molpharmaceut.8b00010
State	Published - Mar 15 2018

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Financial support from the King Abdullah University of Science and Technology (KAUST) is acknowledged with thanks. The authors would like to thank Dr. Rachid Sougrat (KAUST Imaging and Characterization Core Lab) for his invaluable assistance with cryo-TEM.

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title = "A Novel Poly(vinylidene fluoride)-Based 4-Miktoarm Star Terpolymer: Synthesis and Self-Assembly",

abstract = "A well-defined amphiphilic miktoarm polymer incorporating poly(vinylidene fluoride) (PVDF), polystyrene (PS), and poly(ethylene glycol) (PEG) blocks was synthesized via a combination of atom-transfer radical polymerization (ATRP), iodine transfer radical polymerization (ITP), and copper-catalyzed azide-alkyne cycloaddition (CuAAC). Morphology and self-assembly of this star polymer were examined in organic solvents and in water. The aggregates formed in water were found to possess unusual frustrated topology due to immiscibility of PS and PVDF. The polymer was evaluated for transport of small hydrophobic molecules in water.",

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note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: Financial support from the King Abdullah University of Science and Technology (KAUST) is acknowledged with thanks. The authors would like to thank Dr. Rachid Sougrat (KAUST Imaging and Characterization Core Lab) for his invaluable assistance with cryo-TEM.",

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AU - Patil, Yogesh Raghunath

AU - Bilalis, Panagiotis

AU - Polymeropoulos, George

AU - Almahdali, Sarah

AU - Hadjichristidis, Nikos

AU - Rodionov, Valentin

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: Financial support from the King Abdullah University of Science and Technology (KAUST) is acknowledged with thanks. The authors would like to thank Dr. Rachid Sougrat (KAUST Imaging and Characterization Core Lab) for his invaluable assistance with cryo-TEM.

PY - 2018/3/15

Y1 - 2018/3/15

N2 - A well-defined amphiphilic miktoarm polymer incorporating poly(vinylidene fluoride) (PVDF), polystyrene (PS), and poly(ethylene glycol) (PEG) blocks was synthesized via a combination of atom-transfer radical polymerization (ATRP), iodine transfer radical polymerization (ITP), and copper-catalyzed azide-alkyne cycloaddition (CuAAC). Morphology and self-assembly of this star polymer were examined in organic solvents and in water. The aggregates formed in water were found to possess unusual frustrated topology due to immiscibility of PS and PVDF. The polymer was evaluated for transport of small hydrophobic molecules in water.

AB - A well-defined amphiphilic miktoarm polymer incorporating poly(vinylidene fluoride) (PVDF), polystyrene (PS), and poly(ethylene glycol) (PEG) blocks was synthesized via a combination of atom-transfer radical polymerization (ATRP), iodine transfer radical polymerization (ITP), and copper-catalyzed azide-alkyne cycloaddition (CuAAC). Morphology and self-assembly of this star polymer were examined in organic solvents and in water. The aggregates formed in water were found to possess unusual frustrated topology due to immiscibility of PS and PVDF. The polymer was evaluated for transport of small hydrophobic molecules in water.

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SP - 3005

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JO - Molecular Pharmaceutics

JF - Molecular Pharmaceutics

IS - 8

ER -

A Novel Poly(vinylidene fluoride)-Based 4-Miktoarm Star Terpolymer: Synthesis and Self-Assembly

Abstract

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