A New Thiophene-Appended Fluorescein-Hydrazone-Based Chromo-Fluorogenic Sensor for the Screening of Hg
 2+
 Ions in Real Water Samples

Swapnadip Roy; Tapashree Mondal; Dhananjay Dey; Manoj Vasisht Mane; Sujit S. Panja

doi:10.1002/slct.202102692

A New Thiophene-Appended Fluorescein-Hydrazone-Based Chromo-Fluorogenic Sensor for the Screening of Hg 2+ Ions in Real Water Samples

Swapnadip Roy, Tapashree Mondal, Dhananjay Dey, Manoj Vasisht Mane, Sujit S. Panja

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A simple yet efficient, Hg2+ selective sensor, based on a fluroescein-thiophene conjugate, namely, (Z)-3′,6′-dihydroxy-2-(((3-methylthiophen-2-yl)methylene)amino)spiro[isoindoline-1,9′-xanthen]-3-one (FT) has been designed and synthesized. The compound was well characterized by analytical techniques such as HR-MS, FTIR, UV-visible absorption, steady-state fluorescence and time-resolved spectrophotometric techniques. Comprehensive analysis demonstrated FTas a highly specific and ultra-sensitive sensor towards Hg2+ ions in presence of several other interfering metal ions in ethanol/H2O (9 : 1, v/v) at pH=7.2 buffered with 10 mM HEPES buffer at room temperature. The complexation of the probe FT with Hg2+ was well confirmed by ESI-MS and FTIR spectral analysis. The detection limit of the probe FT towards Hg2+ was achieved down to 137 nM. The structure of ligand FT and FT-Hg2+ complex were well corroborated by theoretical studies as well. In addition, the FT-Hg2+ complex was found to be reversible in presence of di-sodium EDTA and hence decipher its recyclability capabilities. The significance of the present probe FT lies in its successful application for the detection and quantification of Hg2+ in real water samples and logic gate fabrication for future incorporation in small organic molecule based efficient molecular devices.

Original language	English (US)
Pages (from-to)	10464-10479
Number of pages	16
Journal	ChemistrySelect
Volume	6
Issue number	38
DOIs	https://doi.org/10.1002/slct.202102692
State	Published - Oct 12 2021

Bibliographical note

KAUST Repository Item: Exported on 2021-10-18
Acknowledgements: The authors thankfully acknowledge DST-FIST (SR/FST/CSI- 267/2015 (C)) and NIT Durgapur for creating and providing infrastructural facilities for research. The authors are thankful to IICB Kolkata for the HR-mass spectra analysis. SSP also acknowledge the financial support from DST SERB (EMR/2016/001230 dt.15. 03. 2017).

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@article{ebcceebdf16343c9b1d9ea1be32880d2,

title = "A New Thiophene-Appended Fluorescein-Hydrazone-Based Chromo-Fluorogenic Sensor for the Screening of Hg 2+ Ions in Real Water Samples",

abstract = "A simple yet efficient, Hg2+ selective sensor, based on a fluroescein-thiophene conjugate, namely, (Z)-3′,6′-dihydroxy-2-(((3-methylthiophen-2-yl)methylene)amino)spiro[isoindoline-1,9′-xanthen]-3-one (FT) has been designed and synthesized. The compound was well characterized by analytical techniques such as HR-MS, FTIR, UV-visible absorption, steady-state fluorescence and time-resolved spectrophotometric techniques. Comprehensive analysis demonstrated FTas a highly specific and ultra-sensitive sensor towards Hg2+ ions in presence of several other interfering metal ions in ethanol/H2O (9 : 1, v/v) at pH=7.2 buffered with 10 mM HEPES buffer at room temperature. The complexation of the probe FT with Hg2+ was well confirmed by ESI-MS and FTIR spectral analysis. The detection limit of the probe FT towards Hg2+ was achieved down to 137 nM. The structure of ligand FT and FT-Hg2+ complex were well corroborated by theoretical studies as well. In addition, the FT-Hg2+ complex was found to be reversible in presence of di-sodium EDTA and hence decipher its recyclability capabilities. The significance of the present probe FT lies in its successful application for the detection and quantification of Hg2+ in real water samples and logic gate fabrication for future incorporation in small organic molecule based efficient molecular devices.",

author = "Swapnadip Roy and Tapashree Mondal and Dhananjay Dey and Mane, {Manoj Vasisht} and Panja, {Sujit S.}",

note = "KAUST Repository Item: Exported on 2021-10-18 Acknowledgements: The authors thankfully acknowledge DST-FIST (SR/FST/CSI- 267/2015 (C)) and NIT Durgapur for creating and providing infrastructural facilities for research. The authors are thankful to IICB Kolkata for the HR-mass spectra analysis. SSP also acknowledge the financial support from DST SERB (EMR/2016/001230 dt.15. 03. 2017).",

year = "2021",

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doi = "10.1002/slct.202102692",

language = "English (US)",

volume = "6",

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journal = "ChemistrySelect",

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T1 - A New Thiophene-Appended Fluorescein-Hydrazone-Based Chromo-Fluorogenic Sensor for the Screening of Hg 2+ Ions in Real Water Samples

AU - Roy, Swapnadip

AU - Mondal, Tapashree

AU - Dey, Dhananjay

AU - Mane, Manoj Vasisht

AU - Panja, Sujit S.

N1 - KAUST Repository Item: Exported on 2021-10-18 Acknowledgements: The authors thankfully acknowledge DST-FIST (SR/FST/CSI- 267/2015 (C)) and NIT Durgapur for creating and providing infrastructural facilities for research. The authors are thankful to IICB Kolkata for the HR-mass spectra analysis. SSP also acknowledge the financial support from DST SERB (EMR/2016/001230 dt.15. 03. 2017).

PY - 2021/10/12

Y1 - 2021/10/12

N2 - A simple yet efficient, Hg2+ selective sensor, based on a fluroescein-thiophene conjugate, namely, (Z)-3′,6′-dihydroxy-2-(((3-methylthiophen-2-yl)methylene)amino)spiro[isoindoline-1,9′-xanthen]-3-one (FT) has been designed and synthesized. The compound was well characterized by analytical techniques such as HR-MS, FTIR, UV-visible absorption, steady-state fluorescence and time-resolved spectrophotometric techniques. Comprehensive analysis demonstrated FTas a highly specific and ultra-sensitive sensor towards Hg2+ ions in presence of several other interfering metal ions in ethanol/H2O (9 : 1, v/v) at pH=7.2 buffered with 10 mM HEPES buffer at room temperature. The complexation of the probe FT with Hg2+ was well confirmed by ESI-MS and FTIR spectral analysis. The detection limit of the probe FT towards Hg2+ was achieved down to 137 nM. The structure of ligand FT and FT-Hg2+ complex were well corroborated by theoretical studies as well. In addition, the FT-Hg2+ complex was found to be reversible in presence of di-sodium EDTA and hence decipher its recyclability capabilities. The significance of the present probe FT lies in its successful application for the detection and quantification of Hg2+ in real water samples and logic gate fabrication for future incorporation in small organic molecule based efficient molecular devices.

AB - A simple yet efficient, Hg2+ selective sensor, based on a fluroescein-thiophene conjugate, namely, (Z)-3′,6′-dihydroxy-2-(((3-methylthiophen-2-yl)methylene)amino)spiro[isoindoline-1,9′-xanthen]-3-one (FT) has been designed and synthesized. The compound was well characterized by analytical techniques such as HR-MS, FTIR, UV-visible absorption, steady-state fluorescence and time-resolved spectrophotometric techniques. Comprehensive analysis demonstrated FTas a highly specific and ultra-sensitive sensor towards Hg2+ ions in presence of several other interfering metal ions in ethanol/H2O (9 : 1, v/v) at pH=7.2 buffered with 10 mM HEPES buffer at room temperature. The complexation of the probe FT with Hg2+ was well confirmed by ESI-MS and FTIR spectral analysis. The detection limit of the probe FT towards Hg2+ was achieved down to 137 nM. The structure of ligand FT and FT-Hg2+ complex were well corroborated by theoretical studies as well. In addition, the FT-Hg2+ complex was found to be reversible in presence of di-sodium EDTA and hence decipher its recyclability capabilities. The significance of the present probe FT lies in its successful application for the detection and quantification of Hg2+ in real water samples and logic gate fabrication for future incorporation in small organic molecule based efficient molecular devices.

UR - http://hdl.handle.net/10754/672871

UR - https://onlinelibrary.wiley.com/doi/10.1002/slct.202102692

U2 - 10.1002/slct.202102692

DO - 10.1002/slct.202102692

M3 - Article

SN - 2365-6549

VL - 6

SP - 10464

EP - 10479

JO - ChemistrySelect

JF - ChemistrySelect

IS - 38

ER -

A New Thiophene-Appended Fluorescein-Hydrazone-Based Chromo-Fluorogenic Sensor for the Screening of Hg 2+ Ions in Real Water Samples

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