A highly enantioselective Brønsted acid catalyst for the Strecker reaction

Magnus Rueping; Erli Sugiono; Cengiz Azap

doi:10.1002/anie.200504344

A highly enantioselective Brønsted acid catalyst for the Strecker reaction

Magnus Rueping^*, Erli Sugiono, Cengiz Azap

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

199 Scopus citations

Abstract

(Chemical Equation Presented) An amenable route to amino acids: An optimized new chiral binol phosphate catalyst (see scheme; Ar = 9-phenanthryl) for the hydrocyanation of imines provides a convenient strategy for the enantioselective synthesis of α-amino acids and diamines.

Original language	English (US)
Pages (from-to)	2617-2619
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	16
DOIs	https://doi.org/10.1002/anie.200504344
State	Published - Apr 10 2006
Externally published	Yes

Keywords

Amino acids
Binol phosphate
Brønsted acids
Organocatalysis
Strecker reaction

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.200504344

Cite this

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title = "A highly enantioselective Br{\o}nsted acid catalyst for the Strecker reaction",

abstract = "(Chemical Equation Presented) An amenable route to amino acids: An optimized new chiral binol phosphate catalyst (see scheme; Ar = 9-phenanthryl) for the hydrocyanation of imines provides a convenient strategy for the enantioselective synthesis of α-amino acids and diamines.",

keywords = "Amino acids, Binol phosphate, Br{\o}nsted acids, Organocatalysis, Strecker reaction",

author = "Magnus Rueping and Erli Sugiono and Cengiz Azap",

year = "2006",

month = apr,

day = "10",

doi = "10.1002/anie.200504344",

language = "English (US)",

volume = "45",

pages = "2617--2619",

journal = "Angewandte Chemie - International Edition",

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T1 - A highly enantioselective Brønsted acid catalyst for the Strecker reaction

AU - Rueping, Magnus

AU - Sugiono, Erli

AU - Azap, Cengiz

PY - 2006/4/10

Y1 - 2006/4/10

N2 - (Chemical Equation Presented) An amenable route to amino acids: An optimized new chiral binol phosphate catalyst (see scheme; Ar = 9-phenanthryl) for the hydrocyanation of imines provides a convenient strategy for the enantioselective synthesis of α-amino acids and diamines.

AB - (Chemical Equation Presented) An amenable route to amino acids: An optimized new chiral binol phosphate catalyst (see scheme; Ar = 9-phenanthryl) for the hydrocyanation of imines provides a convenient strategy for the enantioselective synthesis of α-amino acids and diamines.

KW - Amino acids

KW - Binol phosphate

KW - Brønsted acids

KW - Organocatalysis

KW - Strecker reaction

UR - http://www.scopus.com/inward/record.url?scp=33646559779&partnerID=8YFLogxK

U2 - 10.1002/anie.200504344

DO - 10.1002/anie.200504344

M3 - Article

C2 - 16544358

AN - SCOPUS:33646559779

SN - 1433-7851

VL - 45

SP - 2617

EP - 2619

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 16

ER -

A highly enantioselective Brønsted acid catalyst for the Strecker reaction

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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