A combined mechanistic and computational study of the gold(I)-catalyzed formation of substituted indenes

Pierrick Nun; Sylvain Gaillard; Albert Poater; Luigi Cavallo; Steven P. Nolan

doi:10.1039/c0ob00758g

A combined mechanistic and computational study of the gold(I)-catalyzed formation of substituted indenes

Pierrick Nun, Sylvain Gaillard, Albert Poater, Luigi Cavallo, Steven P. Nolan

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Substituted indenes can be prepared after a sequence [1,3] O-acyl shift-hydroarylation-[1,3] O-acyl shift. Each step is catalyzed by a cationic NHC-Gold(i) species generated in situ after reaction between [(IPr)AuOH] and HBF₄·OEt₂. This interesting silver-free way is fully supported by a computational study justifying the formation of each intermediate.

Original language	English (US)
Pages (from-to)	101-104
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	9
Issue number	1
DOIs	https://doi.org/10.1039/c0ob00758g
State	Published - Jan 1 2011
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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abstract = "Substituted indenes can be prepared after a sequence [1,3] O-acyl shift-hydroarylation-[1,3] O-acyl shift. Each step is catalyzed by a cationic NHC-Gold(i) species generated in situ after reaction between [(IPr)AuOH] and HBF4·OEt2. This interesting silver-free way is fully supported by a computational study justifying the formation of each intermediate.",

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AU - Cavallo, Luigi

AU - Nolan, Steven P.

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AB - Substituted indenes can be prepared after a sequence [1,3] O-acyl shift-hydroarylation-[1,3] O-acyl shift. Each step is catalyzed by a cationic NHC-Gold(i) species generated in situ after reaction between [(IPr)AuOH] and HBF4·OEt2. This interesting silver-free way is fully supported by a computational study justifying the formation of each intermediate.

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AN - SCOPUS:78650158120

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A combined mechanistic and computational study of the gold(I)-catalyzed formation of substituted indenes

Abstract

ASJC Scopus subject areas

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