A chemical approach to "rewire" neural progenitor cells

Min Zu Wu, Mo Li, Guang Hui Liu, Juan Carlos Izpisua Belmonte*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Generation of neural progenitor cells (NPCs) from pluripotent stem cells including ESCs and iPSCs and derivation of NPCs from somatic tissues have been considered promising approaches that could be used therapeutically to restore function in patients suffering neurodegenerative diseases. A new study published in Cell Research shows, for the first time, the generation of NPCs from somatic cells by small molecule compounds under hypoxia without exogenous transcription factors.

Original languageEnglish (US)
Pages (from-to)641-642
Number of pages2
JournalCell research
Issue number6
StatePublished - Jun 2014
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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