3D printing of microlenses for aberration correction in GRIN microendoscopes

Andrea Antonini, Serena Bovetti, Claudio Moretti, Francesca Succol, Vijayakumar P. Rajamanickam, Andrea Bertoncini, Tommaso Fellin, Carlo Liberale

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Two-photon fluorescence microscopy provides high resolution information on the anatomy and function of cellular structures located several hundreds of microns deep within biological tissues. However, light scattering poses a fundamental limit to imaging of deeper areas (> 1.5 mm). Implantable microendoscopic probes based on graded index (GRIN) lenses are widely used tools to perform two-photon fluorescence microscopy in otherwise inaccessible regions[1], but the optical performances of with these probes are limited by intrinsic aberrations.
Original languageEnglish (US)
Title of host publicationThe European Conference on Lasers and Electro-Optics, CLEO_Europe 2017
PublisherOptica Publishing Group (formerly OSA)
ISBN (Electronic)9781509067367
ISBN (Print)9781509067367
StatePublished - 2017
EventThe European Conference on Lasers and Electro-Optics, CLEO_Europe 2017 - Munich, Germany
Duration: Jun 25 2017Jun 29 2017

Publication series

NameOptics InfoBase Conference Papers
VolumePart F82-CLEO_Europe 2017

Conference

ConferenceThe European Conference on Lasers and Electro-Optics, CLEO_Europe 2017
Country/TerritoryGermany
CityMunich
Period06/25/1706/29/17

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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