Research output per year
Research output per year
Personal profile
Research Overview
Dr. Muhammad has broad interests in various epigenetic regulatory systems such as Polycomb group proteins (PcG), noncoding RNAs (ncRNA), nuclear RNAi, and histone marks. He obtained Ph.D., from the University of Strasbourg, where he studied the role of histone variant (CENP-A) in epigenetic specification of centromeres. Dr. Muhammad continued his postdoctoral work at the IGBMC, where he studied the role of CENP-A modifications in cell division. Currently in KAUST, he is focusing on different projects like:
- To understand the role of ncRNAs in epigenetic regulation and chromatin organization
- To uncover the function of chromatin associated RNAi machinery in mammalian cells
- To explore the link between gene regulation and proteins that write, read and erase histone marks in normal development versus stress condition.
Key Research Areas
Gene expression regulation, ncRNA, Chromatin associated RNA.
Education
Molecular and Cellular Biology, Ph.D. , Université de Strasbourg
2012
Biotechnology, B.S., University of Malakand
2006
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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An open-source, automated, and cost-effective platform for COVID-19 diagnosis and rapid portable genomic surveillance using nanopore sequencing
Ramos-Mandujano, G., Grünberg, R., Zhang, Y., Bi, C., Guzmán-Vega, F. J., Shuaib, M., Gorchakov, R. V., Xu, J., Tehseen, M., Takahashi, M., Takahashi, E., Dada, A., Ahmad, A. N., Hamdan, S. M., Pain, A., Arold, S. T. & Li, M., Dec 2023, In: Scientific Reports. 13, 1, 20349.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages
Subudhi, A. K., Green, J. L., Satyam, R., Salunke, R. P., Lenz, T., Shuaib, M., Isaioglou, I., Abel, S., Gupta, M., Esau, L., Mourier, T., Nugmanova, R., Mfarrej, S., Shivapurkar, R., Stead, Z., Rached, F. B., Ostwal, Y., Sougrat, R., Dada, A. & Kadamany, A. F. & 8 others, , Nov 2023, In: Nature Microbiology. 8, 11, p. 2154-2169 16 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity
Shuaib, M., Adroub, S., Mourier, T., Mfarrej, S., Zhang, H., Esau, L., Alsomali, A., Alofi, F. S., Ahmad, A. N., Shamsan, A., Khogeer, A., Hashem, A. M., Almontashiri, N. A. M., Hala, S. & Pain, A., Dec 2023, In: Genome medicine. 15, 1, 54.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load
Mourier, T., Shuaib, M., Hala, S., Mfarrej, S., Alofi, F., Naeem, R., Alsomali, A., Jorgensen, D., Subudhi, A. K., Ben Rached, F., Guan, Q., Salunke, R. P., Ooi, A., Esau, L., Douvropoulou, O., Nugmanova, R., Perumal, S., Zhang, H., Rajan, I. & Al-Omari, A. & 16 others, , Dec 2022, In: Nature Communications. 13, 1, 601.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Ago1 controls myogenic differentiation by regulating eRNA-mediated CBP-guided epigenome reprogramming
Fallatah, B., Shuaib, M., Adroub, S., Paytuví-Gallart, A., Della Valle, F., Nadeef, S. S., Lanzuolo, C. & Orlando, V., Nov 2021, In: Cell Reports. 37, 9, p. 110066Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Rapid single-molecule detection of COVID-19 and MERS antigens via nanobody-functionalized organic electrochemical transistors
Guo, K., Wustoni, S., Koklu, A., Díaz-Galicia, E., Moser, M., Hama, A., Alqahtani, A. A., Ahmad, A. N., Alhamlan, F. S., Shuaib, M., Pain, A., McCulloch, I., Arold, S. T., Grunberg, R. & Inal, S., May 24 2021, In: Nature Biomedical Engineering.Research output: Contribution to journal › Article › peer-review
270 Scopus citations -
Nuclear AGO1 Regulates Gene Expression by Affecting Chromatin Architecture in Human Cells.
Shuaib, M., Parsi, K. M., Thimma, M., Adroub, S., Kawaji, H., Seridi, L., Ghosheh, Y., Fort, A., Fallatah, B., Ravasi, T., Carninci, P. & Orlando, V., Oct 21 2019, In: Cell systems. 9, 5, p. 446-458.e6 457999555 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells
Liu, P., Shuaib, M., Zhang, H., Nadeef, S. & Orlando, V., Dec 19 2019, In: Epigenetics and Chromatin. 12, 1, 78.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations
Press/Media
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Data from King Abdullah University of Science and Technology (KAUST) Advance Knowledge in COVID-19 (An open-source, automated, and cost-effective platform for COVID-19 diagnosis and rapid portable genomic surveillance using nanopore sequencing)
Hamdan, S., Takahashi, M., Pain, A., Arold, S., Tehseen, M., Shuaib, M., Grunberg, R., Xu, J., Guzmán-Vega, F. J. & Zhang, Y.
12/11/23
1 item of Media coverage
Press/Media: Press / Media
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Study finds link between Covid-19 mutations and high immune responses
09/30/23
1 item of Media coverage
Press/Media: Press / Media
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COVID-19 Mutations and Their Links to Excessive Immune Responses
09/29/23
2 items of Media coverage
Press/Media: Press / Media
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Study Finds Link Between Covid-19 Mutations And High Immune Responses
09/28/23
1 item of Media coverage
Press/Media: Press / Media
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Study Finds Link Between Covid-19 Mutations And High Immune Responses
09/28/23
14 items of Media coverage
Press/Media: Press / Media
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Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity
Zhang, H., Pain, A., Adroub, S., Shuaib, M. & Mfarrej, S.
07/21/23
1 item of Media coverage
Press/Media: Press / Media
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Disease severity linked to N protein of SARS-CoV-2
Pain, A., Shuaib, M. & Mfarrej, S.
03/28/22
1 item of Media coverage
Press/Media: Press / Media
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Disease severity linked to N protein of SARS-CoV-2
Pain, A., Shuaib, M. & Mfarrej, S.
03/28/22
3 items of Media coverage
Press/Media: Press / Media