Research output per year
Research output per year
Personal profile
Research Overview
Dr. Fiumelli’s research team applies a variety of cellular and molecular biology tools, transcriptomics, imaging of ion and metabolite dynamics as well as electrophysiology patch-clamp recordings to study the cellular and molecular bases of metabolic and signaling coupling between astrocytes and neurons. Much of our effort is focused on understanding the role of aerobically-derived lactate produced by astrocytes on the plasticity of neuronal networks and on the neuroprotection of neurons in physiological and neurodegenerative conditions.
Key Research Areas
Synaptic plasticity, Brain energy metabolism, Neuro-glial interaction, NMDA receptors, Aerobic glycolysis, Neocortical development.
Research Interests
Biochemistry, Genetics and Molecular Biology • Medicine • Neuroscience • Materials Science • Chemistry • Physics and Astronomy • Pharmacology, Toxicology and Pharmaceutics • Chemical Engineering • Multidisciplinary • Engineering • Immunology and Microbiology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education
Biochemistry, M.S., University of Geneva
Biology, Ph.D. , University of Lausanne
Keywords
- RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Excitatory GABA action is essential for morphological maturation of cortical neurons in vivo
Cancedda, L., Fiumelli, H., Chen, K. & Poo, M. M., May 9 2007, In: Journal of Neuroscience. 27, 19, p. 5224-5235 12 p.Research output: Contribution to journal › Article › peer-review
Open Access334 Scopus citations -
Modulation of GABAergic transmission by activity via postsynaptic Ca 2+-dependent regulation of KCC2 function
Fiumelli, H., Cancedda, L. & Poo, M. M., Dec 8 2005, In: Neuron. 48, 5, p. 773-786 14 p.Research output: Contribution to journal › Article › peer-review
Open Access186 Scopus citations -
Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes
Allaman, I., Fiumelli, H., Magistretti, P. J. & Martin, J. L., Jul 2011, In: Psychopharmacology. 216, 1, p. 75-84 10 p.Research output: Contribution to journal › Article › peer-review
177 Scopus citations -
Role of activity-dependent regulation of neuronal chloride homeostasis in development
Fiumelli, H. & Woodin, M. A., Feb 2007, In: Current Opinion in Neurobiology. 17, 1, p. 81-86 6 p.Research output: Contribution to journal › Review article › peer-review
129 Scopus citations -
Brain-derived neurotrophic factor stimulates energy metabolism in developing cortical neurons
Burkhalter, J., Fiumelli, H., Allaman, I., Chatton, J. Y. & Martin, J. L., Sep 10 2003, In: Journal of Neuroscience. 23, 23, p. 8212-8220 9 p.Research output: Contribution to journal › Article › peer-review
Open Access115 Scopus citations -
Lactate and pyruvate promote oxidative stress resistance through hormetic ROS signaling.
Tauffenberger, A., Fiumelli, H., Almustafa, S. & Magistretti, P. J., Sep 10 2019, In: Cell death & disease. 10, 9Research output: Contribution to journal › Article › peer-review
141 Scopus citations -
Gangliosides: Treatment Avenues in Neurodegenerative Disease.
Magistretti, P. J., Geisler, F. H., Schneider, J. S., Li, P. A., Fiumelli, H. & Sipione, S., Aug 6 2019, In: Frontiers in Neurology. 10, JULResearch output: Contribution to journal › Article › peer-review
82 Scopus citations -
Photo-Chemical Stimulation of Neurons with Organic Semiconductors
Savva, A., Hama, A., Herrera-López, G., Schmidt, T., Migliaccio, L., Steiner, N., Kawan, M., Fiumelli, H., Magistretti, P. J., McCulloch, I., Baran, D., Gasparini, N., Schindl, R., Glowacki, E. D. & Inal, S., Sep 3 2023, In: Advanced Science.Research output: Contribution to journal › Article › peer-review
5 Scopus citations
Press/Media
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King Abdullah University of Science and Technology (KAUST) Reports Findings in Electronics (Photo-Chemical Stimulation of Neurons with Organic Semiconductors)
Magistretti, P., Fiumelli, H., Inal, S., Baran, D., Hama, A., Steiner, N. & Herrera-López, G.
09/19/23
1 item of Media coverage
Press/Media: Press / Media