The primary focus of the Pathogen Genomics Laboratory is to use high-throughput sequencing and other functional genomic technologies to understand the biology and genomic diversity of a few parasitic protists and bacteria with significant impact on human and animal health. Genome and transcriptome sequencing of these organisms is a critical first step towards our understanding of how these organisms grow and thrive in a susceptible host and in other environment. A better understanding of their biology could eventually lead to the development of new intervention strategies. Within this program, a combination of high-throughput DNA and RNA sequencing-based methods, coupled with functional genomics and bioinformatics tools are being used in the following areas of research: Genomics of Apicomplexan parasites and Chromerids and host-parasite interactions. Molecular and genomic characterization of enteric pathogens particularly during mass gatherings Genome variation in Mycobacteria Development of bioinformatic tools for genome-scale data visualization and mining

Genomics