Antibody library design with Transformer and Deep Reinforcement Learning -- source code and data

  • Xiaopeng Xu (Creator)
  • Tiantian Xu (Creator)
  • Juexiao Zhou (Creator)
  • Xingyu Liao (Creator)
  • Ruochi Zhang (Creator)
  • Yu Wang (Creator)
  • Lu Zhang (Creator)
  • Xin Gao (Creator)



This is the source code for AB-Gen, a tool for antibody library design. It can efficiently explore the antibody space and design CDRH3 sequences that fulfill multi-property constraints. Publication: TBA Files included in this release: 1.pipeline.jpg: the workflow of AB-Gen. charlesxu90/ the source code of AB-Gen. the filtered datasets to train the prior model, the pretrained models, and the designed sequences.
Date made availableFeb 20 2023

Cite this